364509
D-色氨酸甲酯 盐酸盐
98%
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关于此项目
经验公式（希尔记法）:
C12H14N2O2 · HCl
化学文摘社编号:
分子量:
254.71
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C12H14N2O2.ClH/c1-16-12(15)10(13)6-8-7-14-11-5-3-2-4-9(8)11;/h2-5,7,10,14H,6,13H2,1H3;1H/t10-;/m1./s1
SMILES string
Cl.COC(=O)[C@H](N)Cc1c[nH]c2ccccc12
InChI key
XNFNGGQRDXFYMM-HNCPQSOCSA-N
assay
98%
optical activity
[α]20/D −18°, c = 5 in methanol
reaction suitability
reaction type: solution phase peptide synthesis
mp
213-216 °C (lit.)
application(s)
peptide synthesis
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Patrick P C Boor et al.
European journal of immunology, 41(6), 1663-1674 (2011-04-07)
Allo-reactive memory T cells are a major barrier for induction of immunological tolerance to allografts in humans. Here, we report that stimulation of unfractionated human T cells with TLR-stimulated allogeneic plasmacytoid dendritic cells (pDCs) induces CD8(+) regulatory T cells (Tregs)
Massoud Akhtari et al.
Epilepsia, 49(8), 1419-1430 (2008-05-16)
The development of nonradioactive and targeted magnetonanoparticles (MNP) capable of crossing the blood-brain barrier (BBB) and of concentrating in the epileptogenic tissues of acute and chronic animal models of temporal lobe epilepsy to render these tissues visible on magnetic resonance
Vijay Narayan Tiwari et al.
Journal of child neurology, 27(5), 598-603 (2011-12-06)
In this study, we determined whether diffusion tensor imaging (DTI), a more widely available imaging modality, is as effective as α-[(11)C]methyl-l-tryptophan (AMT)-positron emission tomography (PET) in localizing epileptogenic tubers in tuberous sclerosis complex. Following that, coregistration of AMT-PET and diffusion
Haruki Nishizawa et al.
The journal of obstetrics and gynaecology research, 34(1), 1-6 (2008-01-30)
We have previously demonstrated that mRNA expression and enzyme activity levels of placental indoleamine 2,3-dioxygenase (IDO), which degrades L-tryptophan and blocks the proliferation of T cells, are significantly low in patients with severe pre-eclampsia. From this observation, we hypothesized that
E D Vasil'eva et al.
Bulletin of experimental biology and medicine, 149(5), 625-627 (2010-12-18)
We studied the effect of 1-methyl-D-tryptophan, an inhibitor of indoleamine-2,3-dioxygenase, on the growth of transplanted hepatocarcinoma-29 in C3HA mice. Hepatocarcinoma-29 transplanted into the thigh muscles undergoes immunological rejection in more than 50% non-syngeneic recipients. Chronic local administration of 1-methyl-D-tryptophan promotes
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