form
beads
reaction suitability
reaction type: solution phase peptide synthesis
particle size
16-50 mesh
capacity
3.8 mmol/g
Application
Azide exchange resin, azide on Amberlite™ IRA-400 is a resin commonly used to replace activated and nonactivated alkyl halides with azide functional group. It has been used in the synthesis of natural products (±)-oxomaritidine and nornicotine.
It can also be used to prepare:
It can also be used to prepare:
- Different imidazolium derived ionic liquid azides.
- An azide synthon 1-(azidomethyl)-4-[18F]-fluorobenzene, which is used to label an amino acid and a neuropeptide using click chemistry.
Legal Information
Amberlite is a trademark of DuPont de Nemours, Inc.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
supp_hazards
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
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Lars C Moeller et al.
Thyroid : official journal of the American Thyroid Association, 19(6), 639-644 (2009-05-19)
Knowledge on the action of thyroid hormone (TH) is augmented by the study of tissue responses to TH in vitro. In order to support the growth of cells in vitro, calf serum (CS) is usually added to the medium to
Synthesis of nornicotine, nicotine and other functionalised derivatives using solid-supported reagents and scavengers
Baxendale IR, et al.
Journal of the Chemical Society. Perkin Transactions 1, 143-154 (2002)
Hassner, A; Stern, M.
Angewandte Chemie (International Edition in English), 25, 478-478 (1986)
Liquid azide salts and their reactions with common oxidizers IRFNA and N2O4
Schneider S, et al.
Inorganic Chemistry, 47(13), 6082-6089 (2008)
New strategy for the preparation of clickable peptides and labeling with 1-(azidomethyl)-4-[18F]-fluorobenzene for PET
Thonon D, et al.
Bioconjugate Chemistry, 20(4), 817-823 (2009)
商品
Since the preparation of the first organic azide, phenyl azide, by Peter Griess in 1864 this energy-rich and versatile class of compounds has enjoyed considerable interest.
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