369527
N,N-二甲基丁胺
99%
别名:
丁基二甲基胺
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关于此项目
线性分子式:
CH3(CH2)3N(CH3)2
化学文摘社编号:
分子量:
101.19
EC Number:
213-156-1
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1731308
MDL number:
InChI key
DJEQZVQFEPKLOY-UHFFFAOYSA-N
InChI
1S/C6H15N/c1-4-5-6-7(2)3/h4-6H2,1-3H3
SMILES string
CCCCN(C)C
assay
99%
bp
93.3 °C/750 mmHg (lit.)
density
0.721 g/mL at 25 °C (lit.)
General description
N,N-二甲基丁胺是叔烷基胺。本文报道了硅（001）表面暴露于N,N- 二甲基丁胺的X射线光电子能谱（XPS）。
Application
N,N -二甲基丁胺适用于制造用于分离蛋白质分子的聚苯乙烯基纳米 LC 整体柱。在涉及比较六种离子对试剂作为寡核苷酸LC / MS流动相改性剂的性能的研究中，该试剂可以用作离子对试剂。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A - STOT SE 3
target_organs
Respiratory system
存储类别
3 - Flammable liquids
wgk
WGK 1
flash_point_f
23.0 °F - closed cup
flash_point_c
-5 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
新产品
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Lingzhi Gong et al.
Rapid communications in mass spectrometry : RCM, 28(4), 339-350 (2014-01-08)
A sensitive and selective liquid chromatography/mass spectrometry (LC/MS) method is essential for quality control of synthetic oligonucleotides. However, researchers are still searching for improvements to ion-pairing reagents for ion-pairing reversed-phase LC/MS. This study performed a comprehensive comparison of six ion-pairing
Anna Kilanowska et al.
Analytical and bioanalytical chemistry, 412(27), 7453-7467 (2020-08-29)
The aim of the present investigation was the analysis and identification of antisense oligonucleotide metabolism products after incubation with human liver microsomes regarding four different oligonucleotide modifications. Separation and detection methods based on the use of liquid chromatography coupled with
Łukasz Nuckowski et al.
The Analyst, 144(15), 4622-4632 (2019-06-28)
Our research focused on applying microextraction by packed sorbent to extracting antisense oligonucleotides from serum samples. The tested sorbents included poly(styrene-co-divinylbenzene), octyl, octadecyl, and unmodified silica gel. As nonpolar sorbents were used for highly-polar molecules, this required ion-pair mode. Comprehensive
Sylwia Studzińska et al.
Analytical and bioanalytical chemistry, 408(6), 1585-1595 (2016-01-14)
Ultra high performance liquid chromatography hyphenated with quadrupole time-of-flight mass spectrometry was used to determine the products of the in vitro metabolism of phosphorothioate oligonucleotides. These compounds may be used during antisense therapy as synthetic fragments of genes. For this
Leta Deressa Tolesa et al.
International journal of biological macromolecules, 130, 818-826 (2019-03-07)
Ammonium-based ionic liquids (ILs): diisopropylethylammonium acetate ([DIPEA][Ac]), diisopropylethylammonium propanoate ([DIPEA][P]) and dimethylbutylammonium acetate ([DMBA][Ac]) are used for the extraction of chitin from shrimp shells. The extracted chitins were characterized by FT-IR, TGA, XRD, SEM and 1H NMR. The yield of
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