371858
6-Methoxy-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole hydrochloride
97%
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关于此项目
经验公式（希尔记法）:
C12H14N2O · HCl
化学文摘社编号:
分子量:
238.71
UNSPSC Code:
12171500
PubChem Substance ID:
MDL number:
InChI
1S/C12H14N2O.ClH/c1-15-8-2-3-11-10(6-8)9-4-5-13-7-12(9)14-11;/h2-3,6,13-14H,4-5,7H2,1H3;1H
SMILES string
Cl[H].COc1ccc2[nH]c3CNCCc3c2c1
InChI key
KRMJEIDSHZEQHJ-UHFFFAOYSA-N
assay
97%
mp
288-290 °C (lit.)
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Sergio Millán-Plano et al.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 17(1), 39-44 (2003-05-21)
The serum concentrations of aluminum, a metal potentially involved in the pathogenesis of Alzheimer's disease, increase with age. Also, intense and prolonged exposure to aluminum may result in dementia. Melatonin and pinoline are two well known antioxidants that efficiently reduce
M Aranda et al.
Journal of pineal research, 49(1), 78-85 (2010-06-08)
The protective in vivo effects of melatonin or pinoline on carbon tetrachloride (CCl(4))-induced oxidative damage were investigated in liver of rats and compared to rats injected only with CCl(4) (5 mL/kg body weight). Hepatic cell membrane fluidity, monitored using fluorescence
J Mekhloufi et al.
Journal of pineal research, 39(1), 27-33 (2005-06-28)
This study aimed at investigating the in vitro protective effects of GWC22, a novel pinoline derivative [6-ethyl-1-(3-methoxyphenyl)-2-propyl-1,2,3,4-tetrahydro-beta-carboline] chlorhydrate, against radiation-induced oxidation of linoleate initiated by hydroxyl radicals ((*)OH). Using linoleate micelles (10(-2) m) as lipid model, two indexes of peroxidation
D L Taylor et al.
Research communications in chemical pathology and pharmacology, 47(1), 133-136 (1985-01-01)
6-MeOTHBC binds to both high and low affinity receptors in human platelets. The beta-carboline is less active than chlorimipramine at the low affinity site, and it is weaker than methysergide, a known 5-HT antagonist, at the high affinity site. The
P T Männistö et al.
Medical biology, 65(5-6), 267-272 (1987-01-01)
Time relationships and mediators of the inhibitory effect of pinealectomy on cold-induced TSH secretion were studied in male Sprague-Dawley rats. Pinealectomy but not sham operation significantly reduced the TSH cold-response (30 min at +4 degrees C) in 6-8 week-old rats
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