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Merck
CN

379700

10-羟基癸酸

technical grade

别名:

NSC 15139

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关于此项目

线性分子式:
HO(CH2)9CO2H
化学文摘社编号:
分子量:
188.26
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
216-848-1
MDL number:
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grade

technical grade

form

solid

impurities

<15% intermolecular dilactone

mp

75-77 °C (lit.)

functional group

carboxylic acid, hydroxyl

SMILES string

OCCCCCCCCCC(O)=O

InChI

1S/C10H20O3/c11-9-7-5-3-1-2-4-6-8-10(12)13/h11H,1-9H2,(H,12,13)

InChI key

YJCJVMMDTBEITC-UHFFFAOYSA-N

General description

10-羟基癸酸 (10-HDA) 是羟基--2-癸烯酸 (10H2DA) 的饱和脂肪酸。其分子有两个官能团(-OH 和-COOH)。据报告,它可以阻止脂多糖诱导的小鼠巨噬细胞 NO 的产生。10-HDA 是从蜜蜂(蜂)的蜂王浆中提取的,具有雌激素操作。 它与聚乙二醇修饰的脂肪酶在透明的苯溶液中通过形成酯键聚合。

Application

10-羟基癸酸适用于研究 Novozym 435 催化的顺式-9,10-环氧-18-羟基十八碳酸的缩聚及其与相应的的 10-羟基癸酸聚合的比较。
反应物参与到:
  • 丙烯酰胺与丙烯酰氧基癸酸钠共聚物的合成
  • 宏观内酯化制备 Sansalvamide A
  • 角质酶催化缩聚反应链长选择性的研究
  • 钌催化酯化,然后大环化
  • 酸酐和酯的合成


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Keita Takahashi et al.
Biomedical research (Tokyo, Japan), 34(4), 205-214 (2013-09-03)
Toll-like receptors (TLRs) play a critical role in innate immunity by recognizing pathogen-associated molecular patterns. Various environmental materials including lipids may affect TLR signaling and modulate innate immune responses. We previously reported that 10-hydroxy-trans-2-decenoic acid (10H2DA) inhibits lipopolysaccharide (LPS)-induced interleukin
Maroula G Kokotou et al.
Metabolites, 10(1) (2020-01-23)
The lipidome of royal jelly (RJ) consists of medium-chained (8-12 carbon atoms) free fatty acids. We present herein a liquid chromatography-high resolution mass spectrometry (HRMS) method that permits the determination of RJ fatty acids and at the same time the
Martin T Gaugg et al.
Journal of breath research, 11(4), 046004-046004 (2017-09-14)
We explore whether real-time breath analysis by high resolution mass spectrometry is suitable to monitor changes at the metabolic level due to inhaling bronchodilator medication. We compared the breath levels of metabolites in a group of patients (n = 50) at baseline



全球贸易项目编号

货号GTIN
379700-500MG04061831951318
379700-5G04061831810721