382213
1-辛基胍半硫酸盐
97%
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关于此项目
线性分子式:
CH3(CH2)7NHC(=NH)NH2 · 1/2H2SO4
化学文摘社编号:
分子量:
220.32
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
97%
InChI
1S/2C9H21N3.H2O4S/c2*1-2-3-4-5-6-7-8-12-9(10)11;1-5(2,3)4/h2*2-8H2,1H3,(H4,10,11,12);(H2,1,2,3,4)
SMILES string
OS(O)(=O)=O.CCCCCCCCNC(N)=N.CCCCCCCCNC(N)=N
InChI key
DTTVLDRWEFQROK-UHFFFAOYSA-N
assay
97%
General description
1-Octylguanidine hemisulfate is a guanidine derivative. Octyl guanidine sulfate is prepared from S-methylisothiourea sulfate and octylamine.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Elías Parra et al.
Molecular and cellular biochemistry, 269(1-2), 19-26 (2005-03-25)
This study shows that the hydrophobic cation octylguanidine protects against myocardial damage induced by ischemia-reperfusion. The protective effect of the amine was analyzed after 5 min of coronary occlusion followed by 5 min reperfusion in rat hearts. ECG tracings from
Natalia Pavón et al.
Endocrine, 35(2), 158-165 (2009-01-27)
Hyperthyroidism sensitizes the heart for reperfusion injury. As known, mitochondrial permeability transition underlies reperfusion heart damage. This study was undertaken to explore the protective effect of octylguanidine (OG), an inhibitor of permeability transition, on hearts from hyperthyroid rats subjected to
G G Re et al.
Bollettino della Societa italiana di biologia sperimentale, 56(6), 619-624 (1980-03-30)
The effects of octylguanidine on electrical activity of Guinea-pig heart were investigated. The substance (2.7 x 10(-4)M) initially reduced the rate of rise of the action potential without a concomitant modification of the other action potential without a concomitant modification
G Beaty et al.
Acta physiologica et pharmacologica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y de la Asociacion Latinoamericana de Farmacologia, 36(3), 217-232 (1986-01-01)
We have studied the inhibitory effects of several cations (OG+, Mg2+, Ca2+, Sr2+, Ba2+, Mn2+, La3+) on the uniport and exchange pathways for Na+ and K+ of rat liver mitochondria. Swelling of mitochondria suspended in sodium or potassium acetates indicates
Y M Galante et al.
Biochemistry, 21(4), 680-687 (1982-02-16)
The methyl 4-azidobenzimidate derivative of the naturally occurring ATPase inhibitor protein (IF1) of mitochondria binds to the beta subunits of soluble F1-ATPase upon photoactivation [Klein, G., Satre, M., Dianoux, A.-C., & Vignais, P. V. (1981) Biochemistry 20, 1339--1344]. A number
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