InChI
1S/C12H21N.ClH/c1-8(13)12-5-9-2-10(6-12)4-11(3-9)7-12;/h8-11H,2-7,13H2,1H3;1H/t8?,9-,10+,11-,12-;
SMILES string
Cl.C[C@H](N)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2
InChI key
OZBDFBJXRJWNAV-MZHJCFSPSA-N
assay
99%
mp
>300 °C (lit.)
functional group
amine
Quality Level
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Guang-Quan Wang et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 98, 275-281 (2012-09-11)
Amantadine hydrochloride (AMA) and rimantadine hydrochloride (RIM) are non-fluorescent in aqueous solutions. This property makes their determination through direct fluorescent method difficult. The competing reactions and the supramolecular interaction mechanisms between the two drugs and coptisine (COP) as they fight
Rafal M Pielak et al.
Structure (London, England : 1993), 19(11), 1655-1663 (2011-11-15)
The M2 channel of influenza A is a target of the adamantane family antiviral drugs. Two different drug-binding sites have been reported: one inside the pore, and the other is a lipid-facing pocket. A previous study showed that a chimera
Belen Puente et al.
Journal of chromatographic science, 49(10), 745-752 (2011-11-15)
A new HPLC procedure with precolumn derivatization and rimantadine as the internal standard for determining memantine, a candidate agent for the treatment of glaucoma in plasma and vitreous humour, has been developed and validated. Precolumn derivatization was performed with 9-fluorenylmethyl-chloroformate-chloride
E I Burtseva et al.
Voprosy virusologii, 57(1), 20-28 (2012-05-26)
The paper gives the results of monitoring the circulation of influenza viruses in the 2010-2011 season, that covers the second year of circulation of pandemic A(H1N1)v virus strains, and their interaction with seasonal A (H3N2) and B strains. Unlike the
Linh Tran et al.
Molecules (Basel, Switzerland), 16(12), 10227-10255 (2011-12-14)
The M2 channel protein on the influenza A virus membrane has become the main target of the anti-flu drugs amantadine and rimantadine. The structure of the M2 channel proteins of the H3N2 (PDB code 2RLF) and 2009-H1N1 (Genbank accession number
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