415057
硬脂酸镁
technical grade
别名:
十八酸 镁盐
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关于此项目
线性分子式:
[CH3(CH2)16CO2]2Mg
化学文摘社编号:
分子量:
591.24
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
209-150-3
Beilstein/REAXYS Number:
3919702
MDL number:
Form:
powder
grade
technical grade
Quality Level
form
powder
composition
palmitate salt, 25% , stearate salt, 65%
mp
200 °C (lit.)
SMILES string
CCCCCCCCCCCCCCCCCC(=O)O[Mg]OC(=O)CCCCCCCCCCCCCCCCC
InChI
1S/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2
InChI key
HQKMJHAJHXVSDF-UHFFFAOYSA-L
General description
硬脂酸镁（Mg-St）是硬脂酸的镁盐。已制备其脱水、二水和三水合物形式。已有研究描述了硬脂酸镁和乳糖颗粒混合片剂的制备。研究了混合时间对压缩片剂硬度、崩解时间和挤出力的影响。硬脂酸镁广泛用作制药工业中的润滑剂。它还在延缓溶解过程中发挥作用。已提出通过激光诱导击穿光谱法检测片剂中的硬脂酸镁。
硬脂酸镁，即硬脂酸的盐，在制药片剂中被广泛用作非活性成分。
硬脂酸镁，即硬脂酸的盐，在制药片剂中被广泛用作非活性成分。
Application
硬脂酸镁可用作双氯芬酸钠片剂处方中的辅料。可用于制备盐酸曲马多骨架片。
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存储类别
11 - Combustible Solids
wgk
nwg
ppe
dust mask type N95 (US), Eyeshields, Gloves
Physical characterization of the polymorphic variations of magnesium stearate and magnesium palmitate hydrate species.
Sharpe SA, et al.
Structural Chemistry, 8(1), 73-84 (1997)
Magnesium stearate, a widely-used food additive, exhibits a lack of in vitro and in vivo genotoxic potential
Hobbs CA, et al.
Toxicology Reports, 4, 554-559 (2017)
Louis St-Onge et al.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 8(2), 272-288 (2005-08-30)
Laser-induced breakdown spectroscopy (LIBS) was evaluated for its potential as a process analytical tool for the rapid determination of magnesium stearate (MgSt) distribution within and between tablets as well as between batches in a typical manufacturing run, and for the
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 415057-1KG | 04061832084480 |
| 415057-25G | 04061832084701 |