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Merck
CN

429066

(3-溴丙氧基)-叔丁基二甲基硅烷

97%

别名:

(3-Bromopropoxy)(1,1-dimethylethyl)dimethylsilane, 1-((tert-Butyldimethylsilyl)oxy)-3-bromopropane, 1-Bromo-3-(tert-butyldimethylsiloxy)propane, 1-Bromo-3-[(tert-butyldimethylsilanyl)oxy]propane, 1-Bromo-3-[(tert-butyldimethylsilyl)oxy]propane, 3-((tert-Butyldimethylsilyl)oxy)-1-bromopropane

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关于此项目

线性分子式:
Br(CH2)3OSi(CH3)2C(CH3)3
化学文摘社编号:
分子量:
253.25
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
97%
Form:
liquid
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Quality Level

assay

97%

form

liquid

contains

sodium carbonate as stabilizer

refractive index

n20/D 1.451 (lit.)

bp

182 °C (lit.)

density

1.093 g/mL at 25 °C (lit.)

functional group

bromo

storage temp.

2-8°C

SMILES string

CC(C)(C)[Si](C)(C)OCCCBr

InChI

1S/C9H21BrOSi/c1-9(2,3)12(4,5)11-8-6-7-10/h6-8H2,1-5H3

InChI key

QGMROEZDWJTIDW-UHFFFAOYSA-N

General description

(3-Bromopropoxy)-tert-butyldimethylsilane is a bromo silyl ether.

Application

(3-Bromopropoxy)-tert-butyldimethylsilane may be used to introduce propanol functionality to many pharmaceuticals.
It may be used as an alkylating agent in the synthesis of the following:
  • N-[2-[N-[3-(tert-butyldimethylsilyloxy)propyl]-N-ethylamino]ethyl]phthalimide
  • O-(3-tert-butyldimethylsilyloxypropyl)-N-(tert-butoxycarbonyl)-L-tyrosine methyl ester
  • tert-butyldimethyl-[3-(3-methyl-2-nitrophenoxy)propoxy]silane


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

185.0 °F - closed cup

flash_point_c

85 °C - closed cup

法规信息

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Major JL, et al.
Inorganic Chemistry, 47(22), 10788-10795 (2008)
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Synthesis of indolo[6,7-a]pyrrolo[3,4-c]carbazoles 1, a new class of cyclin D1/CDK4 inhibitors, by oxidation of the corresponding aryl indolylmaleimides 2, will be described. Two approaches to the synthesis of 2 were identified that required new methods for the synthesis of 7-substituted
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全球贸易项目编号

货号GTIN
429066-5ML04061837015083
429066-25ML04061837015076