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Merck
CN

435430

聚(乙二醇)- 嵌段 - 聚(丙二醇)- 嵌段 - 聚(乙二醇)

average Mn ~2,800

别名:

Pluronic® L-81, PEG-PPG-PEG

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化学文摘社编号:
UNSPSC Code:
12352112
PubChem Substance ID:
NACRES:
NA.23
MDL number:
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InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI key

RVGRUAULSDPKGF-UHFFFAOYSA-N

vapor density

>1 (vs air)

vapor pressure

<0.3 mmHg ( 20 °C)

form

viscous liquid

mol wt

average Mn ~2,800

composition

PEG, 10 wt. %

refractive index

n20/D 1.454

viscosity

475 cP(25 °C, Brookfield)(lit.)

transition temp

softening point −37 °C, cloud point 20 °C (1 wt. % aqueous solution)

density

1.018 g/mL at 25 °C

HLB

1.0 - 7.0

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General description

Pluronic® L-81 是一种脂蛋白分泌抑制剂。

Application

Pluronic® L-81 与 Pluronic F-127 的二元混合物形成二元水凝胶。{12}
软硬表面清洁剂、涂料和水处理中的消泡剂。金属加工润滑剂,线性和交联聚酯及聚氨酯的消泡助剂和增量剂。

Features and Benefits

性质取决于亲水性 (EO)/疏水性 (PO) 比例的表面活性物质EO 含量越高,水包油稳定剂性能越好。

Physical form

末端主要是二羟基官能化低聚物。

Legal Information

Pluronic is a registered trademark of BASF

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Tsz Chung Lai et al.
Colloids and surfaces. B, Biointerfaces, 99, 27-37 (2011-10-18)
Polyplex particles formed with plasmid DNA (pDNA) and Pluronic P85-block-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} (P85-b-P[Asp(DET)]) demonstrated highly effective transfection ability compared to PEG-based block cationomer, PEG-b-P[Asp(DET)]. Ternary polyplexes comprising PEG-b-P[Asp(DET)], poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide)-b-P[Asp(DET)] (P(EPE)-b-P[Asp(DET)]) used as an analog of P85-b-P[Asp(DET)], and pDNA were
Xijun Zhang et al.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 31(6), 842-845 (2011-12-17)
This study examined the effect of P85 (a pluronic block copolymer) and microbubble (MB) ultrasound contrast agents under ultrasound irradiation on gene transfection and expression. The pEGFP plasmids that can encode enhanced green fluorescent protein (pEGFP) served as a report
A N Sklifas et al.
Biofizika, 57(2), 317-324 (2012-05-19)
The adsorption abilities of the perfluorocarbon emulsion stabilized by Proxanol 268 were investigated in vitro and in vivo. In vitro, the saturation point for the blood plasma proteins was nearly reached after five minutes of incubation of the emulsion with
Houjian Gong et al.
Langmuir : the ACS journal of surfaces and colloids, 28(38), 13590-13600 (2012-09-08)
The block polyethers PEO-PPO-ph-PPO-PEO (BPE) and PPO-PEO-ph-PEO-PPO (BEP) are synthesized by anionic polymerization using bisphenol A as initiator. Compared with Pluronic P123, the aggregation behaviors of BPE and BEP at an air/water interface are investigated by the surface tension and
D J Bartley et al.
Veterinary parasitology, 187(3-4), 464-472 (2012-03-21)
Non-specific mechanisms involving ATP-binding cassette drug efflux transporters may play an important role in xenobiotic clearance in ovine gastro-intestinal nematodes. By using transporter inhibitors, the aim of this trial was to assess the possibility of increasing drug bioavailability in the

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