435430
聚（乙二醇）- 嵌段 - 聚（丙二醇）- 嵌段 - 聚（乙二醇）
average Mn ~2,800
别名:
Pluronic® L-81, PEG-PPG-PEG
InChI
1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
InChI key
RVGRUAULSDPKGF-UHFFFAOYSA-N
vapor density
>1 (vs air)
vapor pressure
<0.3 mmHg ( 20 °C)
form
viscous liquid
mol wt
average Mn ~2,800
composition
PEG, 10 wt. %
refractive index
n20/D 1.454
viscosity
475 cP(25 °C, Brookfield)(lit.)
transition temp
softening point −37 °C, cloud point 20 °C (1 wt. % aqueous solution)
density
1.018 g/mL at 25 °C
HLB
1.0 - 7.0
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General description
Pluronic® L-81 是一种脂蛋白分泌抑制剂。
Application
Pluronic® L-81 与 Pluronic F-127 的二元混合物形成二元水凝胶。{12}
软硬表面清洁剂、涂料和水处理中的消泡剂。金属加工润滑剂，线性和交联聚酯及聚氨酯的消泡助剂和增量剂。
Features and Benefits
性质取决于亲水性 (EO)/疏水性 (PO) 比例的表面活性物质EO 含量越高，水包油稳定剂性能越好。
Physical form
末端主要是二羟基官能化低聚物。
Legal Information
Pluronic is a registered trademark of BASF
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Daria Esterházy et al.
Nature, 569(7754), 126-130 (2019-04-17)
The intestinal immune system has the challenging task of tolerating foreign nutrients and the commensal microbiome, while excluding or eliminating ingested pathogens. Failure of this balance leads to conditions such as inflammatory bowel diseases, food allergies and invasive gastrointestinal infections1.
Wei Xu et al.
Drug delivery, 19(4), 208-219 (2012-05-31)
The aim of this study was to construct novel targeting polymeric micelles. Folate-Poly (ethylenimine)-Pluronic copolymers were synthesized. A paclitaxel (PTX)-loaded mixed micelles consisting of Folate-Poly (ethylenimine)-Pluronic and Pluronic L121 copolymers have been developed. The mixed micelles showed nano-sized spherical morphology.
Liyan Zhao et al.
Colloids and surfaces. B, Biointerfaces, 97, 101-108 (2012-05-23)
In this study, curcumin (Cur) loaded mixed micelles (Cur-PF), composed of Pluronic P123 (P123) and Pluronic F68 (F68), was prepared using the thin-film hydration method and evaluated in vitro. The preparation process was optimized with a central composite design (CCD).
Jianan Shen et al.
Biomaterials, 34(5), 1581-1590 (2012-11-14)
The metastasis of breast cancer is the leading cause of cancer death in women, and the lung is a common location of a secondary tumor that has metastasized from the primary source tumor. In this work, an attempt to simultaneously
Irshad A Wani et al.
Colloids and surfaces. B, Biointerfaces, 101, 243-250 (2012-09-27)
Silver nanoparticles have been synthesized in the inverse microemulsions formed using three different surfactants viz., cetyl-trimethyl ammonium bromide (CTAB), Tergitol and Triton X-100. We have done a systematic study of the effect of the surfactants on the particle size and
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Mesoporous materials self-assemble from sol-gel precursors and amphiphiles, forming versatile structures for various applications.
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