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Merck
CN

43667

4-(羟甲基)-D-苯丙氨酸

≥97.0% (HPLC)

别名:

(R)-2-氨基-3-[4-(羟甲基)苯基]丙酸

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经验公式(希尔记法):
C10H13NO3
化学文摘社编号:
分子量:
195.22
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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InChI

1S/C10H13NO3/c11-9(10(13)14)5-7-1-3-8(6-12)4-2-7/h1-4,9,12H,5-6,11H2,(H,13,14)/t9-/m1/s1

SMILES string

N[C@H](Cc1ccc(CO)cc1)C(O)=O

InChI key

OXNUZCWFCJRJSU-SECBINFHSA-N

assay

≥97.0% (HPLC)

application(s)

peptide synthesis

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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E Lempicka et al.
The journal of peptide research : official journal of the American Peptide Society, 53(5), 554-559 (1999-07-29)
This study describes the synthesis and some pharmacological properties of three new analogs of arginine vasopressin (AVP) substituted in position 3 with (R)-alpha-hydroxymethylphenylalanine ([R]-HmPhe). All new peptides were tested for vasopressor and antidiuretic as well as uterotonic activity. None of
M H Kim et al.
International journal of peptide and protein research, 44(5), 457-465 (1994-11-01)
A convenient enantioselective synthesis of p-hydroxymethyl-L-phenylalanine was developed which produces a 4/1 ratio of L/D enantiomers resulting from a chiral phase-transfer-catalyzed alkylation. This amino acid was coupled into the p56(1)ck tyrosine kinase substrate Ac-Leu-Pro-Tyr-Ala-NHCH3 as a replacement for Tyr and
A Olma et al.
Acta biochimica Polonica, 48(4), 1121-1124 (2002-05-09)
To evaluate the role of aromatic amino-acids residues, four analogues of the mu-selective opioid peptide agonist DALDA (H-Tyr-D-Arg-Phe-Lys-NH2) containing the amphiphilic, a,a-disubstituted amino acid (R)- or (S)-alpha-hydroxymethyltyrosine (HmTyr) in position 1 and (R)- or (S)-alpha-hydroxymethylphenylalanine (HmPhe) in position 3 of

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