47306
L-3-氟苯丙氨酸
≥99.0% (sum of enantiomers, HPLC)
别名:
3-氟-L-苯丙氨酸
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关于此项目
经验公式（希尔记法）:
C9H10FNO2
化学文摘社编号:
分子量:
183.18
Beilstein:
2725762
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.22
方案
≥99.0% (sum of enantiomers, HPLC)
旋光性
[α]20/D −25±2°, c = 1% in H2O
反应适用性
reaction type: solution phase peptide synthesis
应用
peptide synthesis
SMILES字符串
N[C@@H](Cc1cccc(F)c1)C(O)=O
InChI
1S/C9H10FNO2/c10-7-3-1-2-6(4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)/t8-/m0/s1
InChI key
VWHRYODZTDMVSS-QMMMGPOBSA-N
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
P Giusti et al.
European journal of pharmacology, 116(3), 287-292 (1985-10-22)
It had previously been shown that D-phenylalanine and hydrocinnamic acid, two in vitro inhibitors of carboxypeptidase A, possess an analgesic action when injected i.p. in mice. We have studied the in vivo effects of indole-3-acetic acid, another carboxypeptidase A inhibitor
Julianne L Kitevski-Leblanc et al.
Journal of biomolecular NMR, 47(2), 113-123 (2010-04-20)
Traditional single site replacement mutations (in this case, phenylalanine to tyrosine) were compared with methods which exclusively employ (15)N and (19)F-edited two- and three-dimensional NMR experiments for purposes of assigning (19)F NMR resonances from calmodulin (CaM), biosynthetically labeled with 3-fluorophenylalanine
M S Chan et al.
Biochemical and biophysical research communications, 219(2), 537-542 (1996-02-15)
Corynebacterium glutamicum was mutated by nitrosoguanidine and five m-fluorophenylalanine (mFP)-resistant mutants were isolated. The mutants were resistant to phenylalanine-mediated feedback inhibition of the prephenate dehydratase activity. Cloning and characterization of the mFP-resistant gene revealed that mutant prephenate dehydratase, encoded by
N Rastogi et al.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 12(12), 954-958 (1993-12-01)
MICs of dapsone (p-p'-diaminodiphenylsulfone) were determined radiometrically for ten strains each of the Mycobacterium avium complex (MAC) and Mycobacterium tuberculosis. MICs ranged from 50 to 250 micrograms/ml for Mycobacterium tuberculosis and from 2 to 100 micrograms/ml for MAC. However, at
W D Kingsbury et al.
Journal of medicinal chemistry, 26(12), 1725-1729 (1983-12-01)
A series of di- and tripeptides containing D- and L-m-fluorophenylalanine was prepared and tested in vitro for the ability to inhibit the growth of the yeast Candida albicans. The results demonstrate that peptides containing L-m-fluorophenylalanine inhibited the growth of C.
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