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Merck
CN

497312

4-哌啶甲醇

97%

别名:

4-羟甲基哌啶

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经验公式(希尔记法):
C6H13NO
化学文摘社编号:
分子量:
115.17
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
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产品名称

4-哌啶甲醇, 97%

InChI

1S/C6H13NO/c8-5-6-1-3-7-4-2-6/h6-8H,1-5H2

SMILES string

OCC1CCNCC1

InChI key

XBXHCBLBYQEYTI-UHFFFAOYSA-N

assay

97%

bp

118-120 °C/10 mmHg (lit.)

mp

55-59 °C (lit.)

functional group

hydroxyl

Quality Level

Application

4-Piperidinemethanol may be used in the preparation of:
  • N-tert-butoxycarbonyl-4-hydroxymethyl piperidine
  • desferrioxamine B (DFO) containing third generation triazine dendrimer
  • ethyl 3-(4-(hydroxymethyl)piperidin-1-yl)propanoate (EHMPP)
  • 4-(hydroxymethyl)piperidine-1-carbodithioic acid (HL)
  • 1-[[(1E)-2-(4-chlorophenyl)ethenyl]sulfonyl]-4-piperidinemethanol
Substrate used in solid-phase organic synthesis of a secondary amine.

General description

4-Piperidinemethanol is a cyclic secondary amine. Its standard molar enthalpies of combustion, sublimation and formation have been determined.

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Skin Corr. 1B

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

230.0 °F - closed cup

flash_point_c

110 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Synthesis and evaluation of 1-arylsulfonyl-3-piperazinone derivatives as factor Xa inhibitor.
Nishida H, et al.
Chemical & Pharmaceutical Bulletin, 49(10), 1237-1244 (2001)
Enzymatic synthesis, thermal and crystalline properties of a poly (β-amino ester) and poly (lactone-co-β-amino ester) copolymers.
Martino L, et al.
Polymer, 53(9), 1839-1848 (2012)
Jongdoo Lim et al.
Bioorganic & medicinal chemistry, 18(15), 5749-5753 (2010-07-10)
The synthesis of a third generation triazine dendrimer, 1, containing multiple, iron-sequestering desferrioxamine B (DFO) groups is described. Benzoylation of the hydroxamic acid groups of DFO and formation of a reactive dichlorotriazine provide the intermediate for reaction with the second
Francis Giraud et al.
Bioorganic & medicinal chemistry letters, 19(2), 301-304 (2008-12-19)
Continuous efforts on the synthesis and structure-activity relationships (SARs) studies of modified 1-benzylamino-2-phenyl-3-(1H-1,2,4-triazol-1-yl)propan-2-ols as antifungal agents, allowed identification of new 1-[(pyridinyl- and piperidinylmethyl)amino] derivatives with MIC(80) values ranging from 1410.0 to 23.0ngmL(-1) on Candidaalbicans. These results confirmed both the importance
Standard molar enthalpies of formation of 2-, 3-, and 4-piperidinomethanol isomers.
da Silva MAVR and Cabral JITA
The Journal of Chemical Thermodynamics, 38(8), 1008-1012 (2006)

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