499137
4-甲基-2-氧代戊酸钠盐
98%
别名:
α-酮异己酸 钠盐, 4-Methyl-2-oxovaleric acid 钠盐, 4-甲基-2-氧代戊酸 钠盐, 酮亮氨酸 钠盐
方案
98%
mp
275 °C (dec.) (lit.)
SMILES字符串
[Na+].CC(C)CC(=O)C([O-])=O
InChI
1S/C6H10O3.Na/c1-4(2)3-5(7)6(8)9;/h4H,3H2,1-2H3,(H,8,9);/q;+1/p-1
InChI key
IXFAZKRLPPMQEO-UHFFFAOYSA-M
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应用
Condensation with α-amino ketones and subsequent cyclization provides pyrazinones.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Heterocycles, 31, 1647-1647 (1990)
D A Roberts et al.
Journal of medicinal chemistry, 33(9), 2326-2334 (1990-09-01)
A series of 1,2,4-triazolo[4,3-a]pyrazine derivatives with human renin inhibitory activity, which incorporate (1S,2S)-2-amino-1,3-dicyclohexyl-1-hydroxypropane, statine (Sta), and (3S,4S)-4-amino-5-cyclohexyl-3-hydroxy-pentanoic acid (ACHPA) transition-state mimetics, have been prepared. Structure-activity relationships for renin inhibitory activity in the series are consistent with the 2-[8-isobutyl-6-phenyl-1,2,4-triazolo[4,3-a]pyrazin-3-yl]-3-(3 pyridyl)propionic acid
William S Crim et al.
Molecular and cellular endocrinology, 323(2), 246-255 (2010-03-10)
The antioxidant and anti-inflammatory compound AGI-1067 (succinobucol) has potential as an oral anti-diabetic agent. AGI-1067 reduces H(b)A1c, improves fasting plasma glucose, and reduces new-onset diabetes. We investigated AGI-1067 for possible effects on mouse pancreatic islets in vitro. Pretreatment with 10
Yuhong Zhu et al.
Enzyme and microbial technology, 49(4), 321-325 (2011-11-25)
This work aims to produce α-ketoisocaproate (KIC) from L-leucine via the free-whole-cell biotransformation of Rhodococcus opacus DSM 43250. The effects of temperature, pH, substrate concentration, cell concentration, and rotating speed on KIC production were examined. Furthermore, the biotransformation conditions were
Benjamin Wax et al.
Journal of dietary supplements, 10(1), 6-16 (2013-01-30)
Glycine-arginine-α-ketoisocaproic acid (GAKIC) has been proposed to increase anaerobic high-intensity exercise performance in male subjects. However, the effects of GAKIC ingestion in female subjects have not been studied. Therefore, the purpose of this study was to investigate the effects of
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