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528099

8-氨基-6-甲氧基喹啉氢溴酸盐

Name: 8-氨基-6-甲氧基喹啉氢溴酸盐
Brand: ALDRICH

97%

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关于此项目

经验公式（希尔记法）:

C₁₀H₁₀N₂O · HBr

化学文摘社编号:

312693-53-1

分子量:

255.11

NACRES:

NA.22

PubChem Substance ID:

24874668

UNSPSC Code:

12352100

MDL number:

MFCD02683506

Assay:

97%

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属性

assay

97%

mp

238 °C (dec.) (lit.)

SMILES string

Br.COc1cc(N)c2ncccc2c1

InChI

1S/C10H10N2O.BrH/c1-13-8-5-7-3-2-4-12-10(7)9(11)6-8;/h2-6H,11H2,1H3;1H

InChI key

WGYQQCWLZRGIKB-UHFFFAOYSA-N

说明

General description

8-Amino-6-methoxyquinoline hydrobromide is a quinoline building block. It is formed during the synthesis of α-morpholino-β-(N-8-amino-6-methoxyquinoline)-benzylacetophenone.

Application

8-Amino-6-methoxyquinoline hydrobromide may be used as an amino component in a novel series of bladder-selective diaminocyclobutenedione potassium channel openers. It may also be used for the synthesis of 1-N-(6-methoxy-8-quinoyl)-4′-carboxyl-benzensulfonamide.

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Butera JA.

Journal of Medicinal Chemistry, 43, 1187-1187 (2000)

Armer RE, et al.

Bioorganic & Medicinal Chemistry, 9, 2430-2430 (1999)

Zn2+ dependent DNA binders based on terminally modified peptide nucleic acids.

Iris Boll et al.

Bioorganic & medicinal chemistry letters, 16(10), 2781-2785 (2006-02-24)

Two ligand-intercalator-peptide nucleic acid conjugates (L-NADI-PNAs) have been synthesized. Affinity of these conjugates to their complementary DNAs was found to be affected by Zn(2+). The magnitude of this effect could be controlled by a variation of the ligand. Upon binding

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货号	GTIN
528099-1G	04061826258347