Quality Level
assay
97%
mp
65-69 °C (lit.)
SMILES string
Cc1cc(N)n(C)n1
InChI
1S/C5H9N3/c1-4-3-5(6)8(2)7-4/h3H,6H2,1-2H3
InChI key
ZFDGMMZLXSFNFU-UHFFFAOYSA-N
General description
5-Amino-1,3-dimethylpyrazole undergoes cyclocondensation with ethyl acetoacetate to form the corresponding tetrahydropyrazolopyridine derivatives.
Application
5-Amino-1,3-dimethylpyrazole may be used in the preparation of:
- 5-benzamido-1,3-dimethylpyrazole
- diethyl 2-{[(1,3-dimethyl-1H-pyrazol-5-yl)amino]methylene}malonate
- 5-amino-1,3-dimethyl-4-phthalidylpyrazole
- (E)-N-(3,7-dimethylocta-2,6-dienyl)-1,3-dimethyl-1H-pyrazol-5-amine analog(LQFM002)
- 4-isopropyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-ol
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
190.4 °F - closed cup
flash_point_c
88 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
The reaction of o?phthalaldchydic acid with 5?amino?1,3?dimethylpyrazole.
Swett LR and Aynilian GH.
Journal of Heterocyclic Chemistry, 12(6), 1135-1136 (1975)
1,3-Oxazines and related compounds. II.1) Ring contraction reaction of 1, 3-oxazin-4-one derivatives into 1,2,4-triazoles and pyrazoles.
Yamamoto, et al.
Chemical & Pharmaceutical Bulletin, 26(6), 1825-1831 (1978)
E A Costa et al.
Life sciences, 92(3), 237-244 (2013-01-09)
The current study describes the synthesis and pharmacological evaluation of (E)-N-(3,7-dimethylocta-2,6-dienyl)-1,3-dimethyl-1H-pyrazol-5-amine (LQFM002), a compound originally designed through a molecular simplification strategy from 4-nerolidylcatechol. LQFM002 was evaluated for preservation of the PLA(2) enzyme inhibitory effects of the lead compound, 4-nerolidylcatechol, using
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 532223-10G | 04061832993751 |