538515
芬布芬
96%
别名:
γ-氧-(1,1′-联苯)-4-丁酸
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关于此项目
线性分子式:
C6H5C6H4CO(CH2)2CO2H
化学文摘社编号:
分子量:
254.28
UNSPSC Code:
41121813
PubChem Substance ID:
EC Number:
252-979-0
MDL number:
InChI key
ZPAKPRAICRBAOD-UHFFFAOYSA-N
InChI
1S/C16H14O3/c17-15(10-11-16(18)19)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-9H,10-11H2,(H,18,19)
SMILES string
OC(=O)CCC(=O)c1ccc(cc1)-c2ccccc2
assay
96%
mp
184-187 °C (lit.)
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signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
新产品
此项目有
P Di Martino et al.
Drug development and industrial pharmacy, 25(10), 1073-1081 (1999-10-26)
Fenbufen is an analgesic, antipyretic and anti-inflammatory drug that is characterized by poor water solubility, a defect increased by very low wettability. Poor water solubility, particularly at low pH, could decrease absorption in the upper part of the gastrointestinal tract
Ho-Lien Huang et al.
Biomaterials, 34(13), 3355-3365 (2013-02-07)
This study is concerned with the development of an agent for single photon emission computer tomography (SPECT) for imaging inflammation and tumor progression. [(123)I]Iodooctyl fenbufen amide ([(123)I]IOFA) was prepared from the precursor N-octyl-4-oxo-4-(4'-(trimethylstannyl)biphenyl-4-yl)butanamide with a radiochemical yield of 15%, specific
C Mardones et al.
Electrophoresis, 22(3), 484-490 (2001-03-22)
A new, automatic method for the clean-up, preconcentration, separation, and quantitation of nonsteroidal anti-inflammatory drugs (NSAIDs) in biological samples (human urine and serum) using solid-phase extraction coupled on-line to capillary electrophoresis is proposed. Automatic pretreatment is carried out by using
Bingxin Li et al.
International journal of pharmaceutics, 287(1-2), 89-95 (2004-11-16)
Layered double hydroxides (LDHs) or so-called anionic clays consist of cationic brucite-like layers and exchangeable interlayer anions. Because of their biocompatibility, these layered inorganic solids can be used as host materials to create drug-LDH host-guest supramolecular structures. Because of the
Z X Meng et al.
Colloids and surfaces. B, Biointerfaces, 84(1), 97-102 (2011-01-14)
Drug (Fenbufen, FBF)-loaded poly(D,L-lactide-co-glycolide) (PLGA) and PLGA/gelatin nanofibrous scaffolds were fabricated via electrospinning technique. The influences of gelatin content, fiber arrangement, crosslinking time and pH value of the buffer solution on FBF release behavior of the resulting nanofibrous scaffolds were
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