538515
芬布芬
96%
别名:
γ-氧-(1,1′-联苯)-4-丁酸
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关于此项目
线性分子式:
C6H5C6H4CO(CH2)2CO2H
化学文摘社编号:
分子量:
254.28
UNSPSC Code:
41121813
PubChem Substance ID:
EC Number:
252-979-0
MDL number:
InChI key
ZPAKPRAICRBAOD-UHFFFAOYSA-N
InChI
1S/C16H14O3/c17-15(10-11-16(18)19)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-9H,10-11H2,(H,18,19)
SMILES string
OC(=O)CCC(=O)c1ccc(cc1)-c2ccccc2
assay
96%
mp
184-187 °C (lit.)
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signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
新产品
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Ho-Lien Huang et al.
Biomaterials, 34(13), 3355-3365 (2013-02-07)
This study is concerned with the development of an agent for single photon emission computer tomography (SPECT) for imaging inflammation and tumor progression. [(123)I]Iodooctyl fenbufen amide ([(123)I]IOFA) was prepared from the precursor N-octyl-4-oxo-4-(4'-(trimethylstannyl)biphenyl-4-yl)butanamide with a radiochemical yield of 15%, specific
P Di Martino et al.
Drug development and industrial pharmacy, 25(10), 1073-1081 (1999-10-26)
Fenbufen is an analgesic, antipyretic and anti-inflammatory drug that is characterized by poor water solubility, a defect increased by very low wettability. Poor water solubility, particularly at low pH, could decrease absorption in the upper part of the gastrointestinal tract
F Kamali et al.
Antimicrobial agents and chemotherapy, 42(5), 1256-1258 (1998-05-21)
The potential effects of concurrent administration of fenbufen and ciprofloxacin on central nervous system activity in healthy young subjects were investigated by electroencephalography (EEG). Visual analog scales (VAS) were used to assess subjective measures of concentration, vigilance, tension, and irritability.
Asif Husain et al.
European journal of medicinal chemistry, 44(9), 3798-3804 (2009-05-22)
The synthesis of a series of 3-[5-(substituted aryl)-1,3,4-oxadiazol-2-yl]-1-(biphenyl-4-yl)propan-1-ones derived from 4-oxo-4-(biphenyl-4-yl)butanoic acid (fenbufen) is described. The structures of these compounds were supported by IR, (1)H NMR, mass spectrometric data and elemental analysis. These compounds were tested for their antiinflammatory, analgesic
Zehadin Gashi et al.
Journal of pharmaceutical sciences, 98(11), 4216-4228 (2009-08-01)
The present work aims at the application of several methods to explain differences in the physical interaction of some aryl propionic acid derivatives (ibuprofen [IBP], ketoprofen [KET], flurbiprofen [FLU], naproxen [NAP], fenbufen [FEN]) with poly(vinylpyrrolidone) (PVP) K30, stored together at
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