538515
芬布芬
96%
别名:
γ-氧-(1,1′-联苯)-4-丁酸
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关于此项目
线性分子式:
C6H5C6H4CO(CH2)2CO2H
CAS Number:
分子量:
254.28
EC 号:
MDL编号:
UNSPSC代码:
41121813
PubChem化学物质编号:
方案
96%
mp
184-187 °C (lit.)
SMILES字符串
OC(=O)CCC(=O)c1ccc(cc1)-c2ccccc2
InChI
1S/C16H14O3/c17-15(10-11-16(18)19)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-9H,10-11H2,(H,18,19)
InChI key
ZPAKPRAICRBAOD-UHFFFAOYSA-N
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警示用语：
Danger
危险声明
预防措施声明
危险分类
Acute Tox. 3 Oral
储存分类代码
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
新产品
A E Sloboda et al.
Arzneimittel-Forschung, 30(4A), 716-721 (1980-01-01)
gamma-Oxo(1,1'-biphenyl)-4-butanoic acid (fenbufen) was shown to be an orally and parenterally effective nonsteroidal antiinflammatory, analgesic and antipyretic agent in a variety of animal species. Like other clinically active antiinflammatory drugs such as acetylsalicylic acid (ASA), indometacin and phenylbutazone, fenbufen has
Marta Cruz-Vera et al.
Journal of chromatography. A, 1202(1), 1-7 (2008-07-18)
Dynamic liquid-phase microextraction (dLPME) using an ionic liquid as acceptor phase is proposed for the determination of six non-steroidal anti-inflammatory drugs (NSAIDs) in human urine samples for the first time. The extraction is carried out in a simple and automatic
L Rodriguez et al.
International journal of pharmaceutics, 183(2), 133-143 (1999-06-11)
A new atomizer that operates with ultrasonic energy is described. This apparatus is intended to obtain microparticulate drug delivery systems through spray-congealing or spray-drying technologies. In this work, some experimental results are reported on model systems submitted to spray-congealing. The
Daniel Carriazo et al.
Journal of pharmaceutical sciences, 99(8), 3372-3380 (2010-03-17)
This work reports the immobilization of Fenbufen, a nonsteroidal anti-inflammatory drug, into two different hexagonal mesoporous silicas (MCM-41) which exhibit some differences in terms of morphology and pore size, and their behavior as systems for sustained release at pH 7.5.
F Kamali et al.
Antimicrobial agents and chemotherapy, 42(5), 1256-1258 (1998-05-21)
The potential effects of concurrent administration of fenbufen and ciprofloxacin on central nervous system activity in healthy young subjects were investigated by electroencephalography (EEG). Visual analog scales (VAS) were used to assess subjective measures of concentration, vigilance, tension, and irritability.
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