548758
噻唑烷-2-甲酸甲酯 盐酸盐
98%
别名:
噻唑烷-2-羧酸甲酯 盐酸盐
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经验公式（希尔记法）:
C5H9NO2S · HCl
化学文摘社编号:
分子量:
183.66
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
98%
InChI
1S/C5H9NO2S.ClH/c1-8-5(7)4-6-2-3-9-4;/h4,6H,2-3H2,1H3;1H
SMILES string
Cl[H].COC(=O)C1NCCS1
InChI key
YGTQIXUXZVNVKG-UHFFFAOYSA-N
assay
98%
mp
159-163 °C (dec.) (lit.)
functional group
ester, thioether
General description
Thiazolidine-2-carboxylic acid methyl ester hydrochloride is a cyclic secondary amino acid derivative. The thiazolidine-2-carboxylic acid (Thz) moiety can exhibit ACE (angiotensin converting enzyme) inhibitor activity in vivo.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
C J Blankley et al.
Journal of medicinal chemistry, 30(6), 992-998 (1987-06-01)
The synthesis of a series of novel, potent angiotensin converting enzyme (ACE) inhibitors containing saturated bicyclic amino acids in place of proline is described. Octahydroindole-2-carboxylic acid, octahydroisoindole-1-carboxylic acid, and octahydro-3-oxoisoindole-1-carboxylic acid can replace proline in both sulfhydryl and non-sulfhydryl ACE
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