557390
2-氯-4-硝基吡啶
97%
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关于此项目
经验公式（希尔记法）:
C5H3ClN2O2
化学文摘社编号:
分子量:
158.54
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
97%
InChI
1S/C5H3ClN2O2/c6-5-3-4(8(9)10)1-2-7-5/h1-3H
SMILES string
[O-][N+](=O)c1ccnc(Cl)c1
InChI key
LIEPVGBDUYKPLC-UHFFFAOYSA-N
assay
97%
mp
52-56 °C (lit.)
functional group
chloro, nitro
Quality Level
Application
用作四丁铵盐脱硝生成氟代、羟基取代和甲氧基取代吡啶的原料。
2-Chloro-4-nitropyridine may be used to synthesize 2-chloro-4-ethoxypyridine and 4-thiophenoxypyridines.
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Scott D Kuduk et al.
Organic letters, 7(4), 577-579 (2005-02-12)
An efficient method for the synthesis of fluoropyridines via the fluorodenitration reaction is reported. The reaction is mediated by tetrabutylammonium fluoride (TBAF) under mild conditions without undue regard to the presence of water. The fluorodenitration is general for 2- or
Y Morisawa et al.
Journal of medicinal chemistry, 23(12), 1376-1380 (1980-12-01)
Eight nitropyridinesulfonamides and pyridinesulfonamide N-oxides as their bioisosteres were prepared and evaluated for anticoccidial activity. Of these compounds, 2-, 4- and 5-nitropyridine-3-sulfonamides and pyridine-2- and -3-sulfonamide N-oxides were found to be active against Eimeria tenella. Thus, the relative positions, ortho
Stabilised 2, 3-Pyridyne Reactive Intermediates of Exceptional Dienophilicity.
Connon SJ and Hegarty AF.
European Journal of Organic Chemistry, 16, 3477-3483 (2004)
Diels?Alder cycloadditions of stabilised 2, 3-pyridynes.
Connon SJ and Hegarty AF.
Tetrahedron Letters, 42(4), 735-737 (2001)
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