Quality Level
assay
97%
form
solid
mp
154-158 °C (lit.)
SMILES string
Oc1nsc2ccccc12
InChI
1S/C7H5NOS/c9-7-5-3-1-2-4-6(5)10-8-7/h1-4H,(H,8,9)
InChI key
DMSMPAJRVJJAGA-UHFFFAOYSA-N
General description
1,2-苯并异噻唑3(2H)-酮可以通过使2-巯基苯甲酸与二苯基磷酰基叠氮化物反应来合成。
Application
1,2-苯并异噻唑-3(2H)-酮可作为前体合成生物活性更高的1,2-苯并异噻唑啉-3-酮(BIT)。
Disclaimer
本品不可用作全球生物杀灭剂法规监管的生物杀灭剂,包括但不限于:美国联邦杀虫剂、杀菌剂和灭鼠剂法(US EPA′s Federal Insecticide Fungicide and Rodenticide Act)、欧盟生物杀灭剂法规(European Biocidal Products Regulation)、加拿大虫害管理监管机构(Canada’s Pest Management Regulatory Agency)、土耳其生物杀灭剂法规(Turkey’s Biocidal Products Regulation)、韩国生物杀灭剂法(Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR))等。
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signalword
Danger
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1A
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
法规信息
农药列管产品
此项目有
Convenient Synthesis of 1, 2-Benzisothiazol-3 (2H)-ones by Cyclization Reaction
of Acyl Azide
of Acyl Azide
Chiyoda T, et al.
Synlett, 2000(10), 1427-1428 (2000)
Mahalakshmi Vasan et al.
ChemMedChem, 5(12), 2079-2087 (2010-11-06)
A simple steady-state kinetic high-throughput assay was developed for the salicylate synthase MbtI from Mycobacterium tuberculosis, which catalyzes the first committed step of mycobactin biosynthesis. The mycobactins are small-molecule iron chelators produced by M. tuberculosis, and their biosynthesis has been identified
Dengfeng Dou et al.
Bioorganic & medicinal chemistry, 19(19), 5782-5787 (2011-09-10)
A series of broad-spectrum antifungal agents based on the 1,2-benzisothiazol-3(2H)-one scaffold is reported. Preliminary structure-activity relationship studies have established the importance of the presence of the heterocyclic ring, a methyl group, and a phenyl ring for optimal manifestation of antifungal
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 561487-25G | 04061832583518 |
| 561487-5G | 04061832583525 |


