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经验公式(希尔记法):
C5H11NO
化学文摘社编号:
分子量:
101.15
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
229-957-4
Beilstein/REAXYS Number:
102696
MDL number:
产品名称
3-羟基哌啶, ≥98.0% (NT)
InChI
1S/C5H11NO/c7-5-2-1-3-6-4-5/h5-7H,1-4H2
InChI key
BIWOSRSKDCZIFM-UHFFFAOYSA-N
SMILES string
OC1CCCNC1
assay
≥98.0% (NT)
form
solid
mp
57-61 °C
solubility
H2O: 1 g/mL, clear
functional group
hydroxyl
storage temp.
2-8°C
Quality Level
Application
3-Hydroxypiperidine may be used to synthesize the following:
- 2-pyrrolidinone via oxidation with iodosylbenzene
- 1-[2,8-bis(trifluoromethyl)quinolin-4-yl]piperidin-3-ol via reaction with 4-bromoquinoline
Reactant for:
Synthesis of unsymmetrical ureas
Synthesis of piperidine nucleoside analogs
Fluorination reactions
Synthesis of substituted pyridines
Synthesis of unsymmetrical ureas
Synthesis of piperidine nucleoside analogs
Fluorination reactions
Synthesis of substituted pyridines
General description
3-Hydroxypiperidine can be obtained from the reduction of 3-hydroxypyridine.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Katritzky.RA, et al.
Comprehensive Organic Functional Group Transformations II, 1 (1995)
Synthesis of quinoline analogs: search for antimalarial agents
Babu R K, et al.
Monatshefte fur Chemie / Chemical Monthly, 139(2), 179-181 (2008)
Oxidation of 3-hydroxypiperidines with iodosylbenzene in water: Tandem oxidative Grob fragmentation-cyclization reaction
Tada N, et al.
Chemical & Pharmaceutical Bulletin, 52(9), 1143-1144 (2004)
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