方案
95%
杂质
may contain ~5% morpholine
折射率
n20/D 1.4770 (lit.)
沸点
240-241 °C (lit.)
密度
1.049 g/mL at 25 °C (lit.)
SMILES字符串
OCCCN1CCOCC1
InChI
1S/C7H15NO2/c9-5-1-2-8-3-6-10-7-4-8/h9H,1-7H2
InChI key
VZKSLWJLGAGPIU-UHFFFAOYSA-N
应用
4-(3-Hydroxypropyl)morpholine may be used in the synthesis of macrocyclic urea compounds, which can act as potent Chk1 inhibitors.
警示用语：
Danger
危险声明
危险分类
Eye Dam. 1 - Repr. 2 - Skin Corr. 1B
储存分类代码
8A - Combustible corrosive hazardous materials
WGK
WGK 3
闪点(°F)
185.0 °F - closed cup
闪点(°C)
85 °C - closed cup
法规信息
新产品
此项目有
David Johansson et al.
BMC cancer, 9, 67-67 (2009-02-28)
The prerequisite for the potential use of the bacterial toxin verotoxin-1 in the treatment of breast cancer was investigated by first determining the expression of its receptor Gb3 (CD77) in clinical breast cancer tissue specimens. We then examined the cytotoxicity
"Synthesis and in-vitro biological activity of macrocyclic urea Chk1 inhibitors"
Li J, et al.
Bioorganic & Medicinal Chemistry Letters, 17(23), 6499-6504 (2007)
Y Jiang et al.
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Dysregulation of the adipo-osteogenic differentiation balance of mesenchymal stem cells (MSCs), which are common progenitor cells of adipocytes and osteoblasts, has been associated with many pathophysiologic diseases, such as obesity, osteopenia, and several neurodegenerative disorders. Growing evidence suggests that lipid
Weihong Xu et al.
Biochemical and biophysical research communications, 463(4), 545-550 (2015-06-01)
In the current study, we investigated the potential activity of AR-42, a novel histone deacetylase (HDAC) inhibitor, against colon cancer cells. Our in vitro results showed that AR-42 induced ceramide production, exerted potent anti-proliferative and pro-apoptotic activities in established (SW-620 and
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