579602
(R)-(+)-1,2-二硫戊环基-3-戊酸
97%
别名:
(R)-6,8-二硫辛酸, (R)-6,8-硫辛酸
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关于此项目
经验公式（希尔记法）:
C8H14O2S2
化学文摘社编号:
分子量:
206.33
UNSPSC Code:
12352005
PubChem Substance ID:
MDL number:
Assay:
97%
Form:
solid
form
solid
InChI
1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1
InChI key
AGBQKNBQESQNJD-SSDOTTSWSA-N
assay
97%
optical activity
[α]20/D +104°, c = 1 in chloroform
mp
48-52 °C (lit.)
存储类别
11 - Combustible Solids
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Alessandra Antonello et al.
Journal of medicinal chemistry, 48(1), 28-31 (2005-01-07)
To combine in the same molecule alpha(1)-adrenoreceptor blocking and antioxidant properties, compounds 2-5 were designed and synthesized. All compounds were effective alpha(1)-adrenoreceptor antagonists and were tested in both functional and binding assays. In addition, compounds 2 and 5 also displayed
Michela Rosini et al.
Journal of medicinal chemistry, 48(2), 360-363 (2005-01-22)
The coupling of two different pharmacophores, each endowed with different biological properties, afforded the hybrid compound lipocrine (7), whose biological profile was markedly improved relative to those of prototypes tacrine and lipoic acid. Lipocrine is the first compound that inhibits
M Nagamatsu et al.
Diabetes care, 18(8), 1160-1167 (1995-08-01)
To determine whether lipoic acid (LA) will reduce oxidative stress in diabetic peripheral nerves and improve neuropathy. We used the model of streptozotocin-induced diabetic neuropathy (SDN) and evaluated the efficacy of LA supplementation in improving nerve blood flow (NBF), electrophysiology
Darren G Burke et al.
International journal of sport nutrition and exercise metabolism, 13(3), 294-302 (2003-12-13)
Alpha-lipoic acid has been found to enhance glucose uptake into skeletal muscle in animal models. Studies have also found that the co-ingestion of carbohydrate along with creatine increases muscle creatine uptake by a process related to insulin-stimulated glucose disposal. The
A S Loginov et al.
Farmakologiia i toksikologiia, 52(4), 78-82 (1989-07-01)
The features of the pharmacokinetics of preparations of alpha-lipoic acid (lipoic acid, thioctacide) as compared with their pharmacodynamic effects were studied in 125 patients with chronic diffuse diseases of the liver of viral and alcohol etiology. After a single administration
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