579602
(R)-(+)-1,2-二硫戊环基-3-戊酸
97%
别名:
(R)-6,8-二硫辛酸, (R)-6,8-硫辛酸
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关于此项目
经验公式（希尔记法）:
C8H14O2S2
化学文摘社编号:
分子量:
206.33
UNSPSC Code:
12352005
PubChem Substance ID:
MDL number:
Assay:
97%
Form:
solid
form
solid
InChI
1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1
InChI key
AGBQKNBQESQNJD-SSDOTTSWSA-N
assay
97%
optical activity
[α]20/D +104°, c = 1 in chloroform
mp
48-52 °C (lit.)
存储类别
11 - Combustible Solids
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Michela Rosini et al.
Journal of medicinal chemistry, 48(2), 360-363 (2005-01-22)
The coupling of two different pharmacophores, each endowed with different biological properties, afforded the hybrid compound lipocrine (7), whose biological profile was markedly improved relative to those of prototypes tacrine and lipoic acid. Lipocrine is the first compound that inhibits
Alessandra Antonello et al.
Journal of medicinal chemistry, 48(1), 28-31 (2005-01-07)
To combine in the same molecule alpha(1)-adrenoreceptor blocking and antioxidant properties, compounds 2-5 were designed and synthesized. All compounds were effective alpha(1)-adrenoreceptor antagonists and were tested in both functional and binding assays. In addition, compounds 2 and 5 also displayed
Daniel Konrad
Antioxidants & redox signaling, 7(7-8), 1032-1039 (2005-07-07)
Alpha-lipoic acid is a naturally occurring cofactor of mitochondrial dehydrogenase complexes and a potent antioxidant. It can interchange between a reduced form and an oxidized form, thereby displaying reducing (antioxidant) and prooxidant properties, respectively. It is suggested that alpha-lipoic acid
B Steinmann et al.
Helvetica paediatrica acta, 34(6), 589-599 (1979-01-01)
Strychnine, a potent antagonist of glycine was given to twins suffering from nonketotic hyperglycinemia at age 73 hours. Within hours of the onset of treatment favorable effects were observed such as improvements of muscle tone, movements, defense reactions, and probably
T V Semenova et al.
Ukrainskii biokhimicheskii zhurnal (1978), 65(5), 26-30 (1993-09-01)
Effect of lipoic acid, 5,5-dithiobis-2-nitrobenzoic acid, monoiodoacetic acid and cystine on thermal stability of human serum albumin was studied by differential scanning calorimetry and electrophoretic methods. Quantitative estimation of the protective effect of these reagents on resistance of 5% solutions
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