592021
烟酰胺-酰胺-15N
98 atom % 15N, 98% (CP)
别名:
3-吡啶(甲酰胺-15N)
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关于此项目
经验公式（希尔记法）:
C6H615NNO
化学文摘社编号:
分子量:
123.12
UNSPSC Code:
12352202
PubChem Substance ID:
MDL number:
产品名称
烟酰胺-酰胺-15N, 98 atom % 15N, 98% (CP)
InChI
1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)/i7+1
SMILES string
[15NH2]C(=O)c1cccnc1
InChI key
DFPAKSUCGFBDDF-CDYZYAPPSA-N
isotopic purity
98 atom % 15N
assay
98% (CP)
form
solid
technique(s)
mass spectrometry (MS): suitable
color
white
mp
130-132 °C (lit.)
mass shift
M+1
Quality Level
Application
Nicotinamide-(amide-15N) can be utilized in the biosynthesis of nicotinamide adenine dinucleotide (NAD). This product can also be used as an analytical standard.
General description
Nicotinamide (or niacinamide) is an amide form of vitamin B3/nicotinic acid that can be used in a variety of cosmetic and pharmaceutical applications. It is found in meat, fish, nuts, and mushrooms, as well as in some vegetables. It is also a precursor for essential coenzymes.
Packaging
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
302.0 °F - closed cup
flash_point_c
150 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Safety of high-dose nicotinamide: a review
Knip M, et al.
Diabetologia, 43(11), 1337-1345 (2000)
A review of nicotinamide: treatment of skin diseases and potential side effects
Rolfe HM
Journal of Cosmetic Dermatology, 13(4), 324-328 (2014)
Igor Shats et al.
Cell metabolism, 31(3), 564-579 (2020-03-05)
Nicotinamide adenine dinucleotide (NAD), a cofactor for hundreds of metabolic reactions in all cell types, plays an essential role in metabolism, DNA repair, and aging. However, how NAD metabolism is impacted by the environment remains unclear. Here, we report an
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme.
Rong Grace Zhai et al.
Cellular and molecular life sciences : CMLS, 66(17), 2805-2818 (2009-05-19)
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase (NMNAT) has long been known as the master enzyme in NAD biosynthesis in living organisms. A burst of investigations on NMNAT, going beyond enzymology, have paralleled increasing discoveries of key roles played by NAD homeostasis in
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