632724
4-氯苯基硼酸频哪醇酯
97%
别名:
4-(4,4,5,5-四甲基-1,3,2-二氧杂硼烷-2-基)氯苯
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C12H16BClO2
化学文摘社编号:
分子量:
238.52
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352103
MDL number:
InChI
1S/C12H16BClO2/c1-11(2)12(3,4)16-13(15-11)9-5-7-10(14)8-6-9/h5-8H,1-4H3
SMILES string
CC1(C)OB(OC1(C)C)c2ccc(Cl)cc2
InChI key
NYARTXMDWRAVIX-UHFFFAOYSA-N
assay
97%
form
solid
mp
50-55 °C (lit.)
storage temp.
2-8°C
Application
4-Chlorophenylboronic acid pinacol ester can be used as a reagent in Suzuki-Miyaura cross-coupling reaction to form C-C bonds by reacting with different aryl halides over palladium catalysts.
It can also be used as a reactant:
It can also be used as a reactant:
- To prepare 2-(4-chlorophenyl)-4H-chromen-4-one by treating with 4-chromanone via one-pot palladium-catalyzed dehydrogenation and oxidative boron-Heck coupling reaction.
- In the ligand-enabled C-H bond activation reaction in the presence of a palladium catalyst.
- To synthesize biaryl amides via Cu-catalyzed C-H bond coupling of aryl arylamides.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 4
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
>230.0 °F
flash_point_c
> 110 °C
ppe
dust mask type N95 (US), Eyeshields, Gloves
Cu (OAc) 2-catalyzed coupling of aromatic C-H bonds with arylboron reagents
Shang M, et al.
Organic Letters, 16(21), 5666-5669 (2014)
A versatile approach to flavones via a one-pot Pd (II)-catalyzed dehydrogenation/oxidative boron-Heck coupling sequence of chromanones
Lee J, et al.
Organic & Biomolecular Chemistry, 14(2), 777-784 (2016)
Ligand-enabled cross-coupling of C (sp 3)-H bonds with arylboron reagents via Pd (II)/Pd (0) catalysis
Chan KSL, et al.
Nature Chemistry, 6(2), 146-146 (2014)
Enhanced heterogeneously catalyzed Suzuki-Miyaura reaction over SiliaCat Pd (0)
Pandarus V, et al.
Tetrahedron Letters, 54(35), 4712-4716 (2013)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持