634859
3-甲氧基-2-萘酚
97%
别名:
2-羟基-3-甲氧基萘
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关于此项目
线性分子式:
CH3OC10H6OH
化学文摘社编号:
分子量:
174.20
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
InChI
1S/C11H10O2/c1-13-11-7-9-5-3-2-4-8(9)6-10(11)12/h2-7,12H,1H3
SMILES string
COc1cc2ccccc2cc1O
InChI key
SJTNTIRIRIPZDV-UHFFFAOYSA-N
assay
97%
form
solid
mp
107-111 °C (lit.)
Application
3-Methoxy-2-naphthol can be used in the synthesis of a naphthoate ester, which can act like dopamine D4 antagonist.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Nick D Pokorzynski et al.
eLife, 8 (2019-04-03)
During infection, pathogens are starved of essential nutrients such as iron and tryptophan by host immune effectors. Without conserved global stress response regulators, how the obligate intracellular bacterium Chlamydia trachomatis arrives at a physiologically similar 'persistent' state in response to
Design and synthesis of 2-naphthoate esters as selective dopamine D4 antagonists.
I Boyfield et al.
Journal of medicinal chemistry, 39(10), 1946-1948 (1996-05-10)
Nenad Manevski et al.
Drug metabolism and disposition: the biological fate of chemicals, 43(1), 126-139 (2014-10-24)
Although skin is the largest organ of the human body, cutaneous drug metabolism is often overlooked, and existing experimental models are insufficiently validated. This proof-of-concept study investigated phase II biotransformation of 11 test substrates in fresh full-thickness human skin explants
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