contains
0.26-0.35 mmol/g phosphorous, 0.37-0.44 mmol/g palladium
composition
Pd, 1.0 , TPP, 0.8
reaction suitability
core: palladium, reaction type: Buchwald-Hartwig Cross Coupling Reaction, reaction type: Heck Reaction, reaction type: Hiyama Coupling, reaction type: Negishi Coupling, reaction type: Sonogashira Coupling, reaction type: Stille Coupling, reaction type: Suzuki-Miyaura Coupling, reagent type: catalyst
extent of labeling
0.4 mmol/g Pd loading
General description
It is an encapsulated catalyst (EnCat®), wherein palladium acetate and triphenylphosphine (TPP) are microencapsulated within a polyurea matrix, which prevents palladium leaching.
Application
可回收利用的负载化催化剂体系，在 C-C 键的形成和还原过程中可简化钯的除去。
Pd EnCat® TPP30 may be used as a catalyst for the microwave-assisted Sonogashira cross-coupling of:
- Aryl iodides and bromides with terminal alkynes to form the corresponding coupling products under copper-free conditions.
- Bromobenzotriazoles and arylacetylenes in the presence of 1,5-diazabicyclo[5.4.0]undecene-5-ene (DBU) and copper iodide to form 2H-benzo[d][1,2,3]triazole derivatives.
Features and Benefits
The advantages of using Pd EnCat® catalysts are:
- low residual metal levels in crude product
- easy recovery of catalyst
- compatibility of immobilized metal with various ligands to effect C-C bond forming reactions
- safer and easier to handle than Pd/C for hydrogenation
- efficiency and economy gains through recovery and recycling
Other Notes
基质含量 30%
Legal Information
PdEncat 技术已申请国际专利，包括 PCT/GB 02/03135。
EnCat is a registered trademark of Reaxa Ltd.
signalword
Warning
Hazard Classifications
Aquatic Chronic 3 - Carc. 2 - Flam. Sol. 2 - Repr. 2 - STOT RE 2 Oral
target_organs
Liver,Kidney
存储类别
4.1B - Flammable solid hazardous materials
wgk
WGK 3
flash_point_f
-9.4 - -7.6 °F
flash_point_c
-23 - -22 °C
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
易制毒化学品（2类）
此项目有
相关内容
Homogeneous palladium catalysts are widely utilized due to their versatility, reactivity and functional group tolerance.
Pd-EnCatTM TPP30 as a Catalyst for the Generation of Highly Functionalized Aryl-and Alkenyl-Substituted Acetylenes via Microwave-Assisted Sonogashira Type Reactions.
Sedelmeier J, et al.
European Journal of Organic Chemistry, 2009(26), 4412-4420 (2009)
Self-assembly of T-shape 2H-benzo[d][1,2,3]-triazoles. Optical waveguide and photophysical properties.
Torres I, et al.
Royal Society of Chemistry Advances, 6(43), 36544-36553 (2016)
Steven V Ley et al.
Chemical communications (Cambridge, England), (10), 1134-1135 (2002-07-19)
Palladium(II) acetate microencapsulated in polyurea (MC-[Pd]) is an economical and versatile heterogeneous catalyst for a range of phosphine-free cross-coupling reactions in both conventional solvents and supercritical carbon dioxide (scCO2); the catalyst can be recovered by a simple filtration and recycled
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 644706-1G | 04061826733233 |
| 644706-10G | 04061833548738 |
| 644706-100G | 04061833689172 |