658308
吗啉代硼氢化锂 溶液
1 M in THF
反应适用性
reagent type: reductant
浓度
1 M in THF
折射率
n20/D 1.489
密度
0.877 g/mL at 25 °C
储存温度
2-8°C
SMILES字符串
[Li+].C[B-](C)(C)N1CCOCC1
InChI
1S/C4H11BNO.Li/c5-6-1-3-7-4-2-6;/h1-4H2,5H3;/q-1;+1
InChI key
FHKYRXRJDHFNMQ-UHFFFAOYSA-N
应用
在与卤代吡啶类化合物和伯烷基甲磺酸酯类化合物反应的情况下,LAB 可以转移胺部分。
能够还原各种官能团。
警示用语:
Danger
危险分类
Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3 - Water-react 2
靶器官
Respiratory system
补充剂危害
储存分类代码
4.3 - Hazardous materials which set free flammable gases upon contact with water
WGK
WGK 3
闪点(°F)
1.4 °F
闪点(°C)
-17 °C
法规信息
新产品
此项目有
Saikia, P.P.
Synlett, 995-995 (2007)
Fisher, G. B. et al
The Journal of Organic Chemistry, 59, 6378-6378 (1994)
Pasumansky, L. et al
Aldrichimica Acta, 38, 61-61 (2005)
Shannon Thomas et al.
Organic letters, 5(21), 3867-3870 (2003-10-11)
[reaction: see text] Lithium aminoborohydride (LAB) reagents promote the amination of 2-fluoropyridine under mild reaction conditions, providing 2-(dialkylamino)pyridines in excellent yield and purity. Treatment of 2-fluoropyridine with 1.1 equiv of lithium aminoborohydride at room temperature affords complete conversion after 1
S Thomas et al.
Organic letters, 3(24), 3915-3918 (2001-11-27)
Lithium aminoborohydride (LAB) reagents initiate the amination or reduction of alkyl methanesulfonate esters, as dictated by reaction conditions. Alkyl methanesulfonate esters treated with unhindered LABs provide tertiary amines in excellent yield. Reduction to the corresponding alkane is achieved using a
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