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关于此项目
经验公式(希尔记法):
C3H3F3O
化学文摘社编号:
分子量:
112.05
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:
Assay:
97%
Quality Segment
assay
97%
refractive index
n20/D <1.300
bp
25-32 °C
density
1.294 g/mL at 25 °C
functional group
ether, fluoro
storage temp.
2-8°C
SMILES string
FC(F)(F)[C@H]1CO1
InChI
1S/C3H3F3O/c4-3(5,6)2-1-7-2/h2H,1H2/t2-/m1/s1
InChI key
AQZRARFZZMGLHL-UWTATZPHSA-N
Application
(R)-(+)-3,3,3-Trifluoro-1,2-epoxypropane can be used as a substrate to synthesize:
- Substituted trifluoro amino propanols, which are found to be potent inhibitors of cholesteryl ester transfer protein.
- (2R) Trifluoro-(methoxybenzyloxy)-propanol (chiral glycol) by reacting with 4-methoxybenzyl alcohol in the presence of NaH. Chiral glycol intermediate is further utilized for the preparation of trifluoromethyl glycol carbamates as potential monoacylglycerol lipase (MAGL) inhibitors.
signalword
Danger
hcodes
pcodes
Hazard Classifications
Flam. Liq. 1
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
-14.8 °F
flash_point_c
-26 °C
ppe
Eyeshields, Faceshields, Gloves
