681059
2-甲基-6-硝基苯甲酸酐
97%
别名:
MNBA
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关于此项目
经验公式（希尔记法）:
C16H12N2O7
化学文摘社编号:
分子量:
344.28
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352108
MDL number:
产品名称
2-甲基-6-硝基苯甲酸酐, 97%
InChI
1S/C16H12N2O7/c1-9-5-3-7-11(17(21)22)13(9)15(19)25-16(20)14-10(2)6-4-8-12(14)18(23)24/h3-8H,1-2H3
SMILES string
Cc1cccc(c1C(=O)OC(=O)c2c(C)cccc2[N+]([O-])=O)[N+]([O-])=O
InChI key
YEKPNMQQSPHKBP-UHFFFAOYSA-N
assay
97%
form
solid
mp
173-177 °C
functional group
anhydride
ester
nitro
Quality Level
Application
2-甲基-6-硝基苯甲酸酐可用于：
- 作为多功能的内酯化试剂用于制备各种大环内酯天然产物和内酯。
- 作为反应促进剂采用相应的胺和羧酸合成羧酰胺衍生物。
- GRP78 抑制剂 prunustatin A、抗真菌化合物 (3R,16E,20E,23R)-(−)-eushearilide 和防肥胖药四氢利泼斯汀的全合成。
General description
2-甲基-6-硝基苯甲酸酐可用作酰胺、内酯、酯和肽合成中的偶联促进剂。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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ACS omega, 6(5), 3571-3577 (2021-02-16)
A depsipeptidic analogue of FE399 was efficiently synthesized mainly through macrolactamization using 2-methyl-6-nitrobenzoic anhydride (MNBA), and a detailed investigation of the desired 16-membered macrolactam core of FE399 was performed. It was determined that the combination of MNBA and a catalytic
Ryohei Hirano et al.
Journal of mass spectrometry : JMS, 53(8), 665-674 (2018-05-17)
CYP3A phenotyping provides a means for personalized drug therapy. We focused our attention on the plasma 6β-hydroxycortisol (6β-OHF) to cortisol ratio as an index for CYP3A phenotyping. In the present study, we developed a sensitive and reliable method for the
A novel and efficient macrolactonization of ω-hydroxycarboxylic acids using 2-methyl-6-nitrobenzoic anhydride (MNBA)
Shiina S, et al.
Tetrahedron Letters, 43(42), 7535-7539 (2002)
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