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Merck
CN

712256

5-叠氮戊酸

≥97.0%

别名:

5-叠氮缬草酸

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关于此项目

经验公式(希尔记法):
C5H9N3O2
化学文摘社编号:
分子量:
143.14
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1706398
Assay:
≥97.0% (TLC), ≥97.0%, 97.0-103.0% (calc. on dry substance, T)
Form:
liquid
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InChI

1S/C5H9N3O2/c6-8-7-4-2-1-3-5(9)10/h1-4H2,(H,9,10)

SMILES string

OC(=O)CCCCN=[N+]=[N-]

InChI key

SBZDIRMBQJDCLB-UHFFFAOYSA-N

assay

≥97.0% (TLC), ≥97.0%, 97.0-103.0% (calc. on dry substance, T)

form

liquid

availability

available only in USA

loss

≤10% loss on drying

functional group

azide, carboxylic acid

storage temp.

−20°C

Application

5-叠氮戊酸可用于合成:
  • 壳聚糖-聚乙二醇水凝胶(通过叠氮-炔点击化学)
  • 含有大环的5-碘-1,2,3-三唑
  • 可介入三唑环的二价奎宁二聚体(用作糖蛋白 (P-gp) 介导的细胞外流的抑制剂)

Packaging

无底玻璃瓶。内含物装在插入的融合锥内。

pictograms

FlameHealth hazard

signalword

Danger

hcodes

Hazard Classifications

Carc. 1B - Self-react. C

supp_hazards

存储类别

5.2 - Organic peroxides and self-reacting hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Click chemistry-derived bivalent quinine inhibitors of P-glycoprotein-mediated cellular efflux.
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Bioorganic & medicinal chemistry letters, 22(13), 4410-4412 (2012)
Synthesis of 5-iodo-1, 2, 3-triazole-containing macrocycles using copper flow reactor technology.
Bogdan AR, et al.
Organic Letters, 13(15), 4060-4063 (2011)
In situ-forming robust chitosan-poly (ethylene glycol) hydrogels prepared by copper-free azide-alkyne click reaction for tissue engineering.
Truong VX, et al.
Biomaterials Science, 2(2), 167-175 (2014)
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Nucleic Acid Therapeutics (NATs), including siRNAs and AntiSense Oligonucleotides (ASOs), have great potential to drug the undruggable genome. Targeting siRNAs and ASOs to specific cell types of interest has driven dramatic improvement in efficacy and reduction in toxicity. Indeed, conjugation
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