721042
3-羧基-5-硝基苯硼酸
别名:
3-Borono-5-nitrobenzoic acid, 3-羧基-5-硝基苯基硼酸, 5-羧基-3-硝基苯硼酸
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关于此项目
经验公式（希尔记法）:
C7H6BNO6
化学文摘社编号:
分子量:
210.94
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352103
MDL number:
form
solid
Quality Level
mp
248-252 °C
functional group
carboxylic acid, nitro
SMILES string
OB(O)c1cc(cc(c1)[N+]([O-])=O)C(O)=O
InChI
1S/C7H6BNO6/c10-7(11)4-1-5(8(12)13)3-6(2-4)9(14)15/h1-3,12-13H,(H,10,11)
InChI key
WNIFCLWDGNHGMX-UHFFFAOYSA-N
Application
3-Carboxy-5-nitrophenylboronic acid can be used as a reactant to prepare:
- Biaryl derivatives via Suzuki-Miyaura cross-coupling with aryl and heteroaryl halides via the formation of a C-C bond.
- 3-Chloro-5-nitrobenzoic acid via copper-catalyzed chlorination reaction.
- Aryl-clonazepam derivatives by palladium-catalyzed Suzuki Cross-coupling reaction with clonazepam in the presence of Pd as a catalyst.
Reactant for:
Used for:
- Copper-catalyzed chlorination
- Parallel solid-phase synthesis of azabicyclooctylidenemethylbenzamides as μ- and d-opioid agonists
Used for:
- Immobilization of glucose oxidase and acetylcholinesterase on boronic acid-activated silica surfaces
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Copper-catalyzed chlorination of functionalized arylboronic acids
Wu H and Hynes JJ
Organic Letters, 12(6), 1192-1195 (2010)
New biaryl-chalcone derivatives of pregnenolone via Suzuki-Miyaura cross-coupling reaction. Synthesis, CYP17 hydroxylase inhibition activity, QSAR, and molecular docking study
Al-Masoudi NA, et al.
Steroids, 101, 43-50 (2015)
Synthesis of new derivatives of aryl-clonazepam via Suzuki Cross-coupling reaction
Salman MA Al-Hussein and Abdul-Rida NA
European Journal of Chemistry, 7(2), 152-155 (2016)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 721042-5G | 04061832713724 |
| 721042-1G | 04061832855967 |