721778
N,N-二甲基甲酰胺硫酸二甲酯加合物
95%
别名:
DMF-硫酸二甲酯, 甲氧基亚甲基-N,N-二甲基亚胺硫酸甲酯
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关于此项目
经验公式(希尔记法):
C5H13NO5S
化学文摘社编号:
分子量:
199.23
MDL编号:
UNSPSC代码:
12352108
PubChem化学物质编号:
NACRES:
NA.22
方案
95%
表单
liquid
折射率
n20/D 1.459
密度
1.349 g/mL at 25 °C
SMILES字符串
CN(C)C=O.COS(=O)(=O)OC
InChI
1S/C3H7NO.C2H6O4S/c1-4(2)3-5;1-5-7(3,4)6-2/h3H,1-2H3;1-2H3
InChI key
UJKUJXVZLUTEAZ-UHFFFAOYSA-N
应用
DMF-Dimethyl sulfate adduct can be used as a reagent to synthesize:
- 2-azetidinones by a reaction between Schiff bases and substituted acetic acids.
- Dimethylamino methylene derivatives, which can be employed in the preparation of fluoroquinolines and 3-amino-4-cyano pyrazole.
- Cis β-sultams by [2 + 2] annulation of aldimines with sulfonic acids.
警示用语:
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
190.0 °F - closed cup
闪点(°C)
87.8 °C - closed cup
法规信息
新产品
此项目有
New reagents from ?N, N-Dimethyl amino methoxy methylenium methyl sulphate?-Synthesis of 3-Amino-4-cyano pyrazole
Arava VR, et al.
Der Pharma Chemica, 50(14), 178-186 (2010)
[2+ 2] Annulation of Aldimines with Sulfonic Acids: A Novel One-Pot cis-Selective Route to ?-Sultams
R Ankita, et al.
European Journal of Organic Chemistry, 2011(23), 4302-4306 (2011)
DMF-dimethyl sulfate as a new reagent for the synthesis of β-lactams.
Jarrahpour A and Zarei M.
Tetrahedron Letters, 50(14), 1568-1570 (2009)
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