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Merck
CN

724467

Sigma-Aldrich

聚(N-异丙基丙烯酰胺-co－甲基丙烯酸)

methacrylic acid 5 mol %, average Mn 50,000

别名:

功能化聚(N-异丙基丙烯酰胺), 功能化聚丙烯酰胺, 聚(N-异丙基丙烯酰胺), 聚(NIPAM-co-MAA), 聚丙烯酰胺

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关于此项目

线性分子式:
(C6H11NO)m (C4H6O2)n
化学文摘社编号:
151954-97-1
UNSPSC代码:
12162002
NACRES:
NA.23

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表单

powder

分子量

average Mn 50,000

组成

methacrylic acid, 5 mol %

mp

>300 °C

InChI

1S/C6H11NO.C4H6O2/c1-4-6(8)7-5(2)3;1-3(2)4(5)6/h4-5H,1H2,2-3H3,(H,7,8);1H2,2H3,(H,5,6)

InChI key

BGJOTKHBFYMJST-UHFFFAOYSA-N

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应用

智能溶胀/塌陷共聚物，可用作温度和pH敏感材料。
PNIPAM-based Smart Surfaces for Cell Sheet Tissue Engineering

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKBW8511V
MKBD3291

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Tomonori Hayashi et al.
The Analyst, 129(5), 421-427 (2004-04-30)
We synthesized a temperature-responsive polymer, N-(isopropylacrylamide)-methacrylic acid copolymer, to which poly-l-lysine was introduced. The synthesized polymer as well as the parent polymer showed reversible soluble-insoluble changes in response to temperature changes across the lower critical solution temperature at 32 degree
Chun-Liang Lo et al.
Journal of controlled release : official journal of the Controlled Release Society, 104(3), 477-488 (2005-05-25)
New thermo-responsive, pH-responsive, and biodegradable nanoparticles comprised of poly(D,L-lactide)-graft-poly(N-isopropyl acrylamide-co-methacrylic acid) (PLA-g-P(NIPAm-co-MAA)) were developed by grafting biodegradable poly(D,L-lactide) onto N-isopropyl acrylamide and methacrylic acid. A core-shell type nano-structure was formed with a hydrophilic outer shell and a hydrophobic inner core
Ester Chiessi et al.
The journal of physical chemistry. B, 114(25), 8301-8312 (2010-06-05)
Polymer microgels of poly(vinyl alcohol)/poly(methacrylate-co-N-isopropyl acrylamide) showed a thermoresponsive behavior, suitable for application in drug delivery (Biomacromolecules 2009, 10, 1589). In this work molecular dynamics (MD) methods were used to explain which structural aspects are determining for thermoresponsivity and how
Ricardo G Sousa et al.
Journal of controlled release : official journal of the Controlled Release Society, 102(3), 595-606 (2005-02-01)
The loading of an antihypertensive cationic drug, diltiazem hydrochloride (DIL.HCl), into poly(N-isopropylacrylamide) [P(N-iPAAm)], poly(methacrylic acid) [P(MAA)], and their poly[(N-isopropylacrylamide)-co-(methacrylic acid)] P[(N-iPAAm)-co-(MAA)] hydrogels as well as their release behaviour have been investigated. For this purpose, two series of hydrogels have been
Yunlu Dai et al.
ACS nano, 6(4), 3327-3338 (2012-03-23)
In this study, we report a new controlled release system based on up-conversion luminescent microspheres of NaYF(4):Yb(3+)/Er(3+) coated with the smart hydrogel poly[(N-isopropylacrylamide)-co-(methacrylic acid)] (P(NIPAM-co-MAA)) (prepared using 5 mol % of MAA) shell. The hybrid microspheres show bright up-conversion fluorescence
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