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Merck
CN

726583

(S)-(-)-α-甲基苄胺

ChiPros®, produced by BASF, ≥99.0%

别名:

(S)-(-)-1-苯乙胺

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关于此项目

线性分子式:
C6H5CH(CH3)NH2
化学文摘社编号:
分子量:
121.18
Beilstein:
2204907
EC 号:
MDL编号:
UNSPSC代码:
12352116
PubChem化学物质编号:
NACRES:
NA.22
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蒸汽压

0.5 mmHg ( 20 °C)

描述

Drug Control: Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet.

方案

≥99.0% (GC)
≥99.0%

表单

liquid

光学纯度

enantiomeric excess: ≥99.0%

drug control

Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet

折射率

n20/D 1.526 (lit.)

沸点

187 °C (lit.)

密度

0.94 g/mL at 25 °C (lit.)

官能团

amine
phenyl

SMILES字符串

C[C@H](N)c1ccccc1

InChI

1S/C8H11N/c1-7(9)8-5-3-2-4-6-8/h2-7H,9H2,1H3/t7-/m0/s1

InChI key

RQEUFEKYXDPUSK-ZETCQYMHSA-N

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应用

  • The first example of a diastereoselective thio-Ugi reaction: a new synthetic approach to chiral imidazole derivatives.: This research presents a novel diastereoselective thio-Ugi reaction, enabling the synthesis of chiral imidazole derivatives, which are essential in asymmetric synthesis and pharmaceutical intermediates (Gulevich et al., 2007).
  • Synthesis and serotonin receptor affinities of a series of enantiomers of alpha-methyltryptamines: evidence for the binding conformation of tryptamines at serotonin 5-HT1B receptors.: This study investigates the synthesis and serotonin receptor affinities of alpha-methyltryptamine enantiomers, contributing to the understanding of chiral compounds in medicinal chemistry (Nichols et al., 1988).

法律信息

ChiPros is a registered trademark of BASF SE

象形图

Skull and crossbonesCorrosion

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Skin Corr. 1B

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 1

闪点(°F)

158.0 °F - closed cup

闪点(°C)

70 °C - closed cup


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Manuel Algarra et al.
Journal of separation science, 33(2), 143-154 (2009-12-31)
Free fatty acids were derivatized as amides (DFFA) by reaction with (R)-(+)-1-phenylethylamine, using a simple, fast and robust reaction scheme. A HPLC method with diode array and ESI MS detection was developed for the analysis of the derivatized substances. Six
Karim Engelmark Cassimjee et al.
Organic & biomolecular chemistry, 10(28), 5466-5470 (2012-06-13)
For biocatalytic production of pharmaceutically important chiral amines the ω-transaminase enzymes have proven useful. Engineering of these enzymes has to some extent been accomplished by rational design, but mostly by directed evolution. By use of a homology model a key
Shao-Hua Huang et al.
Magnetic resonance in chemistry : MRC, 47(5), 423-427 (2009-02-19)
Two types of chiral analytes, the urea and amide derivatives of alpha-phenylethylamine, were prepared. The effect of inter-molecular hydrogen-bonding interaction on self-discrimination of the enantiomers of analytes has been investigated using high-resolution (1)H NMR. It was found that the urea
Andrew M Kelly et al.
Nature protocols, 3(2), 215-219 (2008-02-16)
A three-component chiral derivatization protocol for determining the enantiopurity of chiral diols by (1)H NMR spectroscopic analysis is described here. The present approach involves the derivatization of 1,2- 1,3- and 1,4-diols with 2-formylphenylboronic acid and enantiopure alpha-methylbenzylamine. This method affords
Alejandra León et al.
Journal of natural products, 75(5), 859-864 (2012-05-12)
The enantiomeric lactams (-)-8, (+)-8, (+)-9, and (-)-9 were formed by the reaction of the dimeric phthalide rac-tokinolide B (rac-3) with (R)-(+)-α-methylbenzylamine and (S)-(-)-α-methylbenzylamine. The absolute configurations of compounds 8 and 9 were assigned by experimental and theoretically calculated electronic

商品

Chiral amines play an important role in stereoselective organic synthesis. They are used directly as resolving agents, building blocks, or chiral auxiliaries.

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