form
solid
mol wt
average Mn 5,500
Application
Novel polymer for development of thermosensitive coated micro/nano materials including thermoresponsive polymeric drug delivery systems. The maleimide functional group can be used to conjugate a variety of biomolecules such as enzymes and DNA to the polymer chain.
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存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
商品
Biomaterials science integrates smart materials into biological research, requiring a deep understanding of biological systems.
Poly(N-isopropylacrylamide), or PNIPAM, is a stimuli-responsive polymer that responds to changes in pH and temperature and has a LCST around 32 C.
By altering the physicochemical properties, smart or intelligent drug delivery systems can be designed to deliver therapeutic molecules on-demand. Learn more about the application of stimuli-responsive materials in drug delivery.
K Fujimoto et al.
Biomacromolecules, 1(4), 515-518 (2001-11-17)
We report a novel drug delivery system for apoptosis induction by a "smart" polymer vehicle possessing thermosensitivity and bioaffinity. The polymer chain was prepared by copolymerization of N-isopropylacrylamide and N-methacryloyloxysuccinimide. Cell-adhesive RGDS peptide was conjugated with the copolymer as a
Safak, M.; Alemdaroglu, F. E.; Li, Y.; Ergen, E.; Hernnann, A.
Advanced Materials, 19, 1499-1499 (2007)
Karina L Heredia et al.
Macromolecules, 42(7), 2360-2367 (2009-01-01)
In this report we describe a straightforward approach to synthesize polymers with end-groups that bind site-specifically to two different proteins. Telechelic biotin, maleimide poly(N-isopropylacrylamide) (pNIPAAm) was synthesized for the formation of streptavidin (SAv)-bovine serum albumin (BSA) polymer conjugates. Reversible addition-fragmentation
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 728632-1G | 04061826742051 |
| 728632-5G | 04061833600474 |