73328
三甲基氰硅烷
technical, ≥95% (GC)
别名:
TMSCN, 氰化三甲基硅烷
登录 查看组织和合同定价。
选择尺寸
关于此项目
线性分子式:
(CH3)3SiCN
化学文摘社编号:
分子量:
99.21
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
231-657-3
Beilstein/REAXYS Number:
1737612
MDL number:
Assay:
≥95% (GC)
Form:
liquid
InChI key
LEIMLDGFXIOXMT-UHFFFAOYSA-N
InChI
1S/C4H9NSi/c1-6(2,3)4-5/h1-3H3
SMILES string
C[Si](C)(C)C#N
grade
technical
assay
≥95% (GC)
form
liquid
refractive index
n20/D 1.392 (lit.)
bp
114-117 °C (lit.)
mp
8-11 °C (lit.)
Quality Level
正在寻找类似产品? 访问 产品对比指南
Application
Trimethylsilyl cyanide (TMSCN) can be used as a reagent in the:
- Cyanosilylation of carbonyl compounds using various catalysts.
- Synthesis of α-aminonitriles by one-pot, three-component Strecker reaction of ketones with various amines using Brønsted acid catalyst.
- Cyanation of aryl halides using palladium-complex as a catalyst.
signalword
Danger
Hazard Classifications
Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Flam. Liq. 2
supp_hazards
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
33.8 °F - closed cup
flash_point_c
1 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
新产品
此项目有
A convenient and efficient procedure for the palladium-catalyzed cyanation of aryl halides using trimethylsilylcyanide
Sundermeier M, et al.
Journal of Organometallic Chemistry, 684(1-2), 50-55 (2003)
Asymmetric addition of trimethylsilyl cyanide to ketones catalyzed by Al (salen)/triphenylphosphine oxide
Kim SS and Kwak Ju M
Tetrahedron, 62(1), 49-53 (2006)
Indium tribromide: a highly effective catalyst for the addition of trimethylsilyl cyanide to ?-hetero-substituted ketones
Bandini M, et al.
Tetrahedron Letters, 42(16), 3041-3043 (2001)
Gang Chen et al.
Organic letters, 10(20), 4573-4576 (2008-09-24)
A convenient and efficient synthesis of alpha-aryl nitriles was developed by direct cyanation of alcohols with TMSCN under the catalysis of Lewis acid. Using 5-10 mol % of InBr3 as the catalyst, a variety of benzylic alcohols can be converted
Zhiguo Zhang et al.
The Journal of organic chemistry, 76(23), 9764-9776 (2011-10-21)
We report a new thiourea-Brønsted acid cooperative catalytic system for the enantioselective cyanosilylation of aldehydes with yields up to 90% and enantioselectivities up to 88%. The addition of an achiral acid was found to be crucial for high asymmetric induction.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持