740292
Vitamin D3 solution
100 μg/mL in ethanol, 97% (CP)
别名:
胆钙化醇 溶液
质量水平
方案
97% (CP)
表单
solution
浓度
100 μg/mL in ethanol
技术
mass spectrometry (MS): suitable
颜色
colorless
mp
-144.0 °C
应用
detection
储存温度
−20°C
SMILES字符串
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C
InChI
1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1
InChI key
QYSXJUFSXHHAJI-YRZJJWOYSA-N
基因信息
human ... VDR(7421)
一般描述
Vitamin D3 is also known as cholecalciferol which promotes the absorption of calcium and phosphorus in the body that regulates bone growth. It is commonly found in humans and animals produced on our skin when exposed to sunlight. It facilitates bone growth and mineralization indirectly by enhancing plasma calcium and phosphorus levels. It is synthesized from 7-dehydrocholesterol, a derivative of cholesterol.
应用
Vitamin D3 is used as an internal analytical standard for the quantitation of vitamin D3 concentration in dietary supplements, fortified foods or within a complex biological matrix using a variety of testing applications.
The active metabolite of vitamin D3 is calcitriol (1,25-dihydroxyvitamin D3) encapsulated into polymeric nanoparticles, which finds the application in vitamin D3-based chemotherapy formulation study and in vitro evaluation.
The active metabolite of vitamin D3 is calcitriol (1,25-dihydroxyvitamin D3) encapsulated into polymeric nanoparticles, which finds the application in vitamin D3-based chemotherapy formulation study and in vitro evaluation.
包装
1 mL in ampule
警示用语：
Danger
危险声明
危险分类
Eye Irrit. 2 - Flam. Liq. 2
储存分类代码
3 - Flammable liquids
WGK
WGK 1
闪点(°F)
57.2 °F - closed cup
闪点(°C)
14.0 °C - closed cup
法规信息
新产品
Photometabolism of 7-dehydrocholesterol to previtamin D3 in skin
Holick, MF, et al.
Biochemical and biophysical research communications, 76(1), 107-114 (1977)
Nano-encapsulation of vitamin D 3 active metabolites for application in chemotherapy: formulation study and in vitro evaluation
Almouazen E, et al.
Pharmaceutical Research, 30(4), 1137-1146 (2013)
Stefan Pilz et al.
Hypertension (Dallas, Tex. : 1979), 65(6), 1195-1201 (2015-03-25)
Vitamin D deficiency is a risk factor for arterial hypertension, but randomized controlled trials showed mixed effects of vitamin D supplementation on blood pressure (BP). We aimed to evaluate whether vitamin D supplementation affects 24-hour systolic ambulatory BP monitoring values
Yuan-Hua Chen et al.
Toxicological sciences : an official journal of the Society of Toxicology, 145(1), 90-97 (2015-02-13)
Several reports demonstrated that maternal lipopolysaccharide (LPS) exposure at middle gestational stage caused neural tube defects (NTDs). This study investigated the effects of supplementation with vitamin D3 (VitD3) during pregnancy on LPS-induced NTDs. Pregnant mice except controls were ip injected
Anders Burild et al.
Steroids, 98, 72-79 (2015-03-01)
Information regarding the endogenous storages of vitamin D3 after cutaneous vitamin D synthesis compared to oral vitamin D3 supplementation is sparse. Furthermore it is not known whether vitamin D3 can be stored for later use during periods of shortages of
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