742783
N-[(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl]-N′-biotinyl-1,8-diamino-3,6-dioxaoctane
for Copper-free Click Chemistry
别名:
(1α,8α,9β)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl N-{2-{2-{{5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno [3,4-d]imidazol-4-yl]pentanamido}ethoxy}ethoxy}ethyl}carbamate, BCN-biotin
反应适用性
reaction type: click chemistry
储存温度
−20°C
SMILES字符串
O=C(CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)NCCOCCOCCNC(=O)OCC3[C@@H]4CCC#CCC[C@H]34
InChI
1S/C27H42N4O6S/c32-24(10-6-5-9-23-25-22(18-38-23)30-26(33)31-25)28-11-13-35-15-16-36-14-12-29-27(34)37-17-21-19-7-3-1-2-4-8-20(19)21/h19-23,25H,3-18H2,(H,28,32)(H,29,34)(H2,30,31,33)/t19-,20+,21-,22-,23-,25-/m0/s1
InChI key
ZYDQEEHFKLOZCS-SSNODSCZSA-N
应用
Cyclooctyne derivative conjugated to biotin. Useful as a biotinylation reagent for labeling azide containing molecules or compounds. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This strained cyclooctyne will react with azide-functionalized compounds without the need for a copper catalyst to result in a stable triazole linkage. Subsequent labeled molecules can be purified using streptavidin or avidin affinity reagents.
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Readily accessible bicyclononynes for bioorthogonal labeling and three-dimensional imaging of living cells.
Jan Dommerholt et al.
Angewandte Chemie (International ed. in English), 49(49), 9422-9425 (2010-09-22)
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