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Merck
CN

750166

聚(N-异丙基丙烯酰胺-co－甲基丙烯酸)

methacrylic acid 10 mol %, average Mn 8,000-10,000

别名:

功能化聚(N-异丙基丙烯酰胺), 功能化聚丙烯酰胺, 聚(N-异丙基丙烯酰胺), 聚(NIPAM-co-MAA), 聚丙烯酰胺

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关于此项目

线性分子式:
(C6H11NO)m (C4H6O2)n
化学文摘社编号:
151954-97-1
UNSPSC Code:
12162002
NACRES:
NA.23

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InChI

1S/C6H11NO.C4H6O2/c1-4-6(8)7-5(2)3;1-3(2)4(5)6/h4-5H,1H2,2-3H3,(H,7,8);1H2,2H3,(H,5,6)

InChI key

BGJOTKHBFYMJST-UHFFFAOYSA-N

mol wt

average Mn 8,000-10,000

composition

methacrylic acid, 10 mol %

mp

>300 °C

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Application

智能溶胀/塌陷共聚物，可用作温度和pH敏感材料。

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKBH5656
MKBH5656V

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Samer R Abulateefeh et al.
Macromolecular bioscience, 11(12), 1722-1734 (2011-10-21)
Many difficulties in treating cancer arise from the problems in directing highly cytotoxic agents to the deseased tissues, cells and intracellular compartments. Many drug delivery systems have been devised to address this problem, including those that show a change in
Pierre Simard et al.
International journal of pharmaceutics, 381(2), 86-96 (2009-05-19)
A promising avenue in cancer therapy using liposomal formulations is the combination of site-specific delivery with triggered drug release. The use of trigger mechanisms in liposomes could be relevant for drugs susceptible to lysosomal hydrolytic/enzymatic degradation. Here, we propose a
J Moselhy et al.
Journal of biomaterials science. Polymer edition, 11(2), 123-147 (2000-03-16)
The pH- and temperature-responsive poly(N-isopropylacrylamide-co-methacrylic acid) (PNIPAm/MAA) nanoparticles are of potential application in targeted drug delivery. Their responsive properties in the presence of human serum albumin were investigated using dynamic light scattering (DLS), protein assay, and electron spin resonance (ESR)
Eunice Costa et al.
Langmuir : the ACS journal of surfaces and colloids, 28(26), 10082-10090 (2012-06-09)
The layer-by-layer (LbL) assembly of polyelectrolyte pairs on temperature and pH-sensitive cross-linked poly(N-isopropylacrylamide)-co-(methacrylic acid), poly(NIPAAm-co-MAA), microgels enabled a fine-tuning of the gel swelling and responsive behavior according to the mobility of the assembled polyelectrolyte (PE) pair and the composition of
Ana M Díez-Pascual et al.
Journal of colloid and interface science, 347(1), 79-89 (2010-04-14)
The confinement of polyelectrolyte multilayers of poly-L-lysine (PLL)/poly-L-glutamic acid (PGA) and chitosan (CHIT)/dextran sulfate (DEX) onto soft and porous thermoresponsive poly(N-isopropylacrylamide-co-methacrylic acid) (P(NiPAM-co-MAA)) microgel was studied by dynamic light scattering (DLS) and electrophoretic measurements. DLS demonstrates an "odd-even" effect in
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