760684
Methyl 4-bromo-2-chloropyridine-3-carboxylate
97%
别名:
Methyl 4-bromo-2-chloronicotinate
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关于此项目
经验公式(希尔记法):
C7H5BrClNO2
化学文摘社编号:
分子量:
250.48
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
方案
97%
表单
solid
mp
54-58 °C
SMILES字符串
COC(=O)c1c(Cl)nccc1Br
InChI
1S/C7H5BrClNO2/c1-12-7(11)5-4(8)2-3-10-6(5)9/h2-3H,1H3
InChI key
FITBMOURWDPXGV-UHFFFAOYSA-N
Christoph Gibson et al.
Journal of medicinal chemistry, 52(14), 4370-4379 (2009-06-26)
Blockade of the bradykinin B(2) receptor provides therapeutic benefit in hereditary angioedema (HAE) and potentially in many other diseases. Herein, we describe the development of highly potent B(2) receptor antagonists with a molecular weight of approximately 500 g/mol. First, known
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