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Merck
CN

763934

5-硝基呋喃-2-丙烯酸

95%

别名:

β-(5-Nitro-2-furyl)acrylic acid, 3-(5-Nitro-2-furanyl)-2-propenoic acid, 5-Nitrofuranacrylic acid

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关于此项目

经验公式(希尔记法):
C7H5NO5
化学文摘社编号:
分子量:
183.12
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
228-488-2
MDL number:
Assay:
95%
Form:
solid
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InChI key

LWOWNIPZHGWKNR-DUXPYHPUSA-N

InChI

1S/C7H5NO5/c9-7(10)4-2-5-1-3-6(13-5)8(11)12/h1-4H,(H,9,10)/b4-2+

SMILES string

OC(=O)\C=C\c1ccc(o1)[N+]([O-])=O

assay

95%

form

solid

mp

238-240 °C

functional group

carboxylic acid, nitro

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A Belicová et al.
Folia microbiologica, 44(5), 513-518 (2000-09-21)
The diethyl ether extracts isolated from unfermented milk and milk fermented by Enterococcus faecium exhibited dose-dependent inhibition of mutagenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG), nitrovin (NIT), 5-nitro-2-furylacrylic acid (NFA) and UV-irradiation on the Ames bacterial test (Salmonella typhimurium strains TA97 and
D Slamenová et al.
Neoplasma, 30(1), 7-12 (1983-01-01)
Induction of 6-thioguanine-resistant mutations was studied in Chinese hamster V79 cells treated with nitrofurylacrylic acid under aerobic and hypoxic conditions. The results obtained demonstrated that the mutagenic activity of this substance, less significant in aerobic conditions, was very high under
H Vojteková et al.
Neoplasma, 33(6), 691-698 (1986-01-01)
Mutagenicity inhibition of MNNG*, NFAA* as well as of nitrovin by ascorbic acid was observed. The influence of ascorbic acid on these compounds was parallelly studied also by spectroscopy. Mutagenicity inhibition was characterized by SOS chromotest. Inhibition degree was evaluated
L S Priputina et al.
Voprosy pitaniia, (4)(4), 58-64 (1990-07-01)
Nitrofurylacrylic acid sodium salt is a substance of moderate toxicity. Its LD50 for male rats after oral administration comprises 1220 mg/kg, for female rats--1400 mg/kg. The minimal toxic dose, in case of long-term administration comprises 14 mg/kg. At the level
M Cerná et al.
Mutation research, 77(1), 13-20 (1980-01-01)
Human blood and urine mutagenicity of 3-(5-nitro-2-furyl)acrylic acid (5-NFA) was analysed by using Salmonella typhimurium indicator strains TA100 AND TA98 and the cytogenetic analysis of human peripheral lymphocytes. 8 human volunteers were given doses of 1 g 5-NFA per os.

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