764213
生物素-PEG4-炔
for copper catalyzed click labeling
别名:
乙炔-PEG4-生物素结合物
登录查看公司和协议定价
关于此项目
经验公式(希尔记法):
C21H35N3O6S
CAS Number:
分子量:
457.58
MDL编号:
UNSPSC代码:
12161502
PubChem化学物质编号:
NACRES:
NA.22
质量水平
方案
95%
表单
solid
反应适用性
reaction type: click chemistry
mp
55-64 °C
储存温度
−20°C
SMILES字符串
O=C(NCCOCCOCCOCCOCC#C)CCCC[C@@H](SC1)[C@@]2([H])[C@]1([H])NC(N2)=O
InChI
1S/C21H35N3O6S/c1-2-8-27-10-12-29-14-15-30-13-11-28-9-7-22-19(25)6-4-3-5-18-20-17(16-31-18)23-21(26)24-20/h1,17-18,20H,3-16H2,(H,22,25)(H2,23,24,26)/t17-,18-,20-/m1/s1
InChI key
SKMJWNZZFUDLKQ-QWFCFKBJSA-N
应用
生物素-PEG4-炔可以通过生物正交叠氮-炔加成反应对 4-叠氮苯丙氨酸 (AzPhe) 丝素蛋白进行改性,以制备光敏性蛋白质材料。
生物素化试剂,采用铜催化的 1,3 偶极环加成点击化学标记含炔烃的分子或生物分子。炔烃基团与叠氮化物反应形成稳定的三唑键,有助于将生物素引入目标炔烃改性体系。
凭借Synple 全自动合成平台(SYNPLE-SC002)自动标记您的生物素
凭借Synple 全自动合成平台(SYNPLE-SC002)自动标记您的生物素
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Ryan T Cassell et al.
Chembiochem : a European journal of chemical biology, 16(7), 1060-1067 (2015-04-01)
The brevetoxins are neurotoxins that are produced by the "Florida red tide" dinoflagellate Karenia brevis. They bind to and activate the voltage-gated sodium channels in higher organisms, specifically the Nav 1.4 and Nav 1.5 channel subtypes. However, the native physiological
Javier Mazuela et al.
Organic letters, 19(20), 5541-5544 (2017-10-06)
The organocatalytic asymmetric transfer hydrogenation of N-alkyl aryl imino esters for the direct synthesis of N-alkylated arylglycinate esters is reported. High yields and enantiomeric ratios were obtained, and tolerance to a diverse set of functional groups facilitated the preparation of
Azide-incorporated clickable silk fibroin materials with the ability to photopattern.
Teramoto H, et al.
ACS biomaterials science & engineering, 2(2), 251-258 (2016)
Masanobu Nagano et al.
Bioorganic & medicinal chemistry, 25(21), 5952-5961 (2017-10-11)
Vaccination is a reliable method of prophylaxis and a crucial measure for public health. However, the majority of vaccines cannot be administered orally due to their degradation in the harsh gut environment or inability to cross the GI tract. In
Maheshika S K Wanigasekara et al.
ACS omega, 3(10), 14229-14235 (2019-08-29)
Modification of arginine residues using dicarbonyl compounds is a common method to identify functional or reactive arginine residues in proteins. Arginine undergoes several kinds of posttranslational modifications in these functional residues. Identifying these reactive residues confidently in a protein or
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持