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Merck
CN

764213

生物素-PEG4-炔

for copper catalyzed click labeling

别名:

乙炔-PEG4-生物素结合物

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关于此项目

经验公式(希尔记法):
C21H35N3O6S
化学文摘社编号:
分子量:
457.58
MDL number:
UNSPSC Code:
12161502
PubChem Substance ID:
NACRES:
NA.22
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Quality Level

assay

95%

form

solid

reaction suitability

reaction type: click chemistry

mp

55-64 °C

storage temp.

−20°C

SMILES string

O=C(NCCOCCOCCOCCOCC#C)CCCC[C@@H](SC1)[C@@]2([H])[C@]1([H])NC(N2)=O

InChI

1S/C21H35N3O6S/c1-2-8-27-10-12-29-14-15-30-13-11-28-9-7-22-19(25)6-4-3-5-18-20-17(16-31-18)23-21(26)24-20/h1,17-18,20H,3-16H2,(H,22,25)(H2,23,24,26)/t17-,18-,20-/m1/s1

InChI key

SKMJWNZZFUDLKQ-QWFCFKBJSA-N

Application

生物素-PEG4-炔可以通过生物正交叠氮-炔加成反应对 4-叠氮苯丙氨酸 (AzPhe) 丝素蛋白进行改性,以制备光敏性蛋白质材料。
生物素化试剂,采用铜催化的 1,3 偶极环加成点击化学标记含炔烃的分子或生物分子。炔烃基团与叠氮化物反应形成稳定的三唑键,有助于将生物素引入目标炔烃改性体系。

凭借Synple 全自动合成平台(SYNPLE-SC002)自动标记您的生物素


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Javier Mazuela et al.
Organic letters, 19(20), 5541-5544 (2017-10-06)
The organocatalytic asymmetric transfer hydrogenation of N-alkyl aryl imino esters for the direct synthesis of N-alkylated arylglycinate esters is reported. High yields and enantiomeric ratios were obtained, and tolerance to a diverse set of functional groups facilitated the preparation of
Azide-incorporated clickable silk fibroin materials with the ability to photopattern.
Teramoto H, et al.
ACS biomaterials science & engineering, 2(2), 251-258 (2016)
Ryan T Cassell et al.
Chembiochem : a European journal of chemical biology, 16(7), 1060-1067 (2015-04-01)
The brevetoxins are neurotoxins that are produced by the "Florida red tide" dinoflagellate Karenia brevis. They bind to and activate the voltage-gated sodium channels in higher organisms, specifically the Nav 1.4 and Nav 1.5 channel subtypes. However, the native physiological



全球贸易项目编号

货号GTIN
764213-10MG04061833230954
764213-5MG04061833230961