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Merck
CN

767239

Sigma-Aldrich

Polyester bis-MPA dendron, 32 hydroxyl, 1 amine

generation 5, 95%

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UNSPSC代码:
12162002
NACRES:
NA.23
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描述

hydroxyl surface groups

方案

95%

表单

solid

分子量

generation 5

特点

focal point amine

表面基团编号

32

mp

>300 °C

储存温度

−20°C

一般描述

Polyester dendritic structures which are based on 2,2-bismethylolpropionic acid (bis-MPA) monomer are highly branched and can be end functionalized with a wide range of functional groups. They are widely used in biosensors, optics, adhesives and coatings. The hydroxyl and amine end surface groups increase the biocompatibility and the scaffolding ability of these dendritic polymers.†

应用

Amine dendrons can be covalently attached through conjugation to carboxyl groups, primary amines, or sulfhydryl groups. Amines can also attach to oxidized carbohydrate groups (usually aldehydes) by reductive amination.

特点和优势

Well-defined structure, high intrinsic drug loading capability, flexibility for tailored functionalization.

其他说明

bis-MPA 即 2,2-二羟甲基丙酸

法律信息

Manufactured by Polymer Factory Sweden AB

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Biocompatible Dendritic Building Blocks for Advanced Biomedical Research
AB, P. F. S.
Material Matters, 7(3), 47-51 (2012)
Magnetic labelled horseradish peroxidase-polymer nanoparticles: A recyclable nanobiocatalyst
Khosravi, A., Vossoughi, M., Shahrokhian, S., & Alemzadeh, I.
J. Serb. Chem. Soc., 78(7), 921-931 (2013)
Omayra L Padilla De Jesús et al.
Bioconjugate chemistry, 13(3), 453-461 (2002-05-16)
High molecular weight polymers (> 20 000 Da) have been widely used as soluble drug carriers to improve drug targeting and therapeutic efficacy. Dendritic polymers are exceptional candidates for the preparation of near monodisperse drug carriers due to their well-defined
Anna Carlmark et al.
Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been

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