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Merck
CN

779717

19-羟基-4-雄甾烯-3,17-二酮

≥90% (HPLC)

别名:

19-羟基雄烯二酮, 4-雄甾烯-3,17-二酮-19-醇

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关于此项目

经验公式(希尔记法):
C19H26O3
化学文摘社编号:
分子量:
302.41
Beilstein:
2567249
EC 号:
MDL编号:
UNSPSC代码:
12352103
PubChem化学物质编号:
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方案

≥90% (HPLC)

表单

crystals

旋光性

[α]/D +190±5°, c = 1 in chloroform

储存温度

−20°C

SMILES字符串

C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34CO)[C@@H]1CCC2=O

InChI

1S/C19H26O3/c1-18-8-7-16-14(15(18)4-5-17(18)22)3-2-12-10-13(21)6-9-19(12,16)11-20/h10,14-16,20H,2-9,11H2,1H3/t14-,15-,16-,18-,19+/m0/s1

InChI key

XGUHPTGEXRHMQQ-BGJMDTOESA-N

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包装

Bottomless glass bottle. Contents are inside inserted fused cone.

象形图

Health hazard

警示用语:

Warning

危险声明

预防措施声明

危险分类

Repr. 2

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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D C Swinney et al.
Archives of biochemistry and biophysics, 305(1), 61-67 (1993-08-15)
Aromatase activity in microsomes from human placenta (HPM) and rat ovary (ROM) was compared by measuring the accumulation of 19-oxygenated intermediates, the effect of tritium substitution upon rates, and the distribution of tritium in products. A considerable accumulation of intermediates
S Ohnishi et al.
Steroids, 55(1), 5-9 (1990-01-01)
19-Hydroxyandrostenedione (19-OHA), highly labeled with deuterium at position 7, was synthesized from unlabeled androstenediol diacetate. The deuterium labels were introduced into the 7-keto compound with dichloroaluminum deuteride to obtain [7-2H2]androstenediol. The labeled androstenediol diacetate was converted to the labeled 19-OHA
Y Osawa et al.
Steroids, 55(4), 165-169 (1990-04-01)
19-Hydroxyandrostenedione (19-OHA) is secreted from the adrenal glands in men and women and also from the placenta during pregnancy. It has been found to cause hypertension in animal models. We have synthesized [7,7-2H2]-19-OHA with high deuterium content and, together with
H Miyashita et al.
Nihon Naibunpi Gakkai zasshi, 66(10), 1117-1125 (1990-10-20)
The conversion of androgen to estrogen is mediated by aromatase activity, and 19-hydroxylase and C10-19lyase are seen to be involved in C19-demethylation. The present study is to demonstrate C10-19lyase activity in adrenal tissue. Fetal bovine and pig adrenal tissue homogenates
H Sekihara et al.
Clinical endocrinology, 39(5), 557-560 (1993-11-01)
We have reported that 19-hydroxyandrostenedione (19-OH-A-dione) functions as an amplifier of the sodium-retaining and hypertensive action of aldosterone. We therefore measured 19-hydroxyandrostenedione in hypertensive patients. We studied 53 normal male control subjects and 63 male patients with essential hypertension (48

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