Name: (4R,4′R,5S,5′S)-2,2′-(1-Methylethylidene
Brand: ALDRICH

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About This Item

经验公式（希尔记法）:

C₃₃H₃₀N₂O₂

CAS Number:

157904-67-1

分子量:

486.60

MDL编号:

MFCD24849939

UNSPSC代码:

12352005

PubChem化学物质编号:

329768502

NACRES:

NA.22

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质量水平

100

方案

95%

表单

solid

mp

164-169 °C

官能团

ether
phenyl

SMILES字符串

CC(C1=N[C@H](C2=CC=CC=C2)[C@H](C3=CC=CC=C3)O1)(C)C4=N[C@H](C5=CC=CC=C5)[C@H](C6=CC=CC=C6)O4

InChI

1S/C33H30N2O2/c1-33(2,31-34-27(23-15-7-3-8-16-23)29(36-31)25-19-11-5-12-20-25)32-35-28(24-17-9-4-10-18-24)30(37-32)26-21-13-6-14-22-26/h3-22,27-30H,1-2H3/t27-,28-,29+,30+/m1/s1

InChI key

ZWWGNCSTEMMQOQ-XAZDILKDSA-N

应用

(4R,4′R,5S,5′S)-2,2′-(1-Methylethylidene) or (4S,5R)-Bis-Phbox) can be used as a ligand:

To prepare selective exo-catalysts for enantioselective 1,3-dipolar cycloaddition reactions.
In the asymmetric aminooxygenation of alkenes in the presence of tetramethylaminopyridyl radical (TEMPO) as an oxidant and copper(II) triflate as a catalyst.
In asymmetric aminofluorination of olefins using an iron catalyst.

This chiral Box ligand was most recently shown to mediate an asymmetric aminofluorination of olefins utlizing Xtalfuor-E (719439) and TREAT-HF (344648). The resulting cyclic carbamates can be readily converted into their concomitant beta-fluoro amino acids.