804258
N-(3-(4-bromophenyl)-propanoyl)-L-homoserine lactone
≥95%
别名:
4-bromo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-benzenepropanamide, LasR and TraR inhibitor, LuxR
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关于此项目
经验公式（希尔记法）:
C13H14BrNO3
化学文摘社编号:
分子量:
312.16
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.22
Assay:
≥95%
Form:
solid
assay
≥95%
form
solid
storage temp.
−20°C
SMILES string
O=C(OCC1)[C@@]1([H])NC(CCC2=CC=C(Br)C=C2)=O
InChI
1S/C13H14BrNO3/c14-10-4-1-9(2-5-10)3-6-12(16)15-11-7-8-18-13(11)17/h1-2,4-5,11H,3,6-8H2,(H,15,16)/t11-/m0/s1
InChI key
SGDZSJUYCLTPRG-NSHDSACASA-N
Application
AHL analog is a strong, broad-spectrum inhibitor of numerous LuxR-type receptors (e.g.: LuxR from Vibrio fischeri, LasR from P. aeruginosa, and TraR from Agrobacterium tumefaciens). This compound represents a good choice for initial testing of LuxR-type receptor inhibition.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
相关内容
We study quorum sensing, how bacteria sense their density. Synthesized compounds modulate pathways, aiding research on infections in various hosts.
Grant D Geske et al.
Chembiochem : a European journal of chemical biology, 9(3), 389-400 (2008-01-29)
Bacterial quorum sensing is mediated by low molecular-weight signals and plays a critical role in both the pathogenesis of infectious disease and beneficial symbioses. There is significant interest in the development of synthetic ligands that can intercept bacterial quorum sensing
Grant D Geske et al.
Journal of the American Chemical Society, 129(44), 13613-13625 (2007-10-12)
Bacteria use a language of low molecular weight ligands to assess their population densities in a process called quorum sensing. This chemical signaling process plays a pivotal role both in the pathogenesis of infectious disease and in beneficial symbioses. There
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| 货号 | GTIN |
|---|---|
| 804258-10MG | 04061833232354 |