804258
N-(3-(4-bromophenyl)-propanoyl)-L-homoserine lactone
≥95%
别名:
4-bromo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-benzenepropanamide, LasR and TraR inhibitor, LuxR
登录查看公司和协议定价
选择尺寸
关于此项目
经验公式（希尔记法）:
C13H14BrNO3
化学文摘社编号:
分子量:
312.16
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.22
方案
≥95%
表单
solid
储存温度
−20°C
SMILES字符串
O=C(OCC1)[C@@]1([H])NC(CCC2=CC=C(Br)C=C2)=O
InChI
1S/C13H14BrNO3/c14-10-4-1-9(2-5-10)3-6-12(16)15-11-7-8-18-13(11)17/h1-2,4-5,11H,3,6-8H2,(H,15,16)/t11-/m0/s1
InChI key
SGDZSJUYCLTPRG-NSHDSACASA-N
应用
AHL analog is a strong, broad-spectrum inhibitor of numerous LuxR-type receptors (e.g.: LuxR from Vibrio fischeri, LasR from P. aeruginosa, and TraR from Agrobacterium tumefaciens). This compound represents a good choice for initial testing of LuxR-type receptor inhibition.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Grant D Geske et al.
Chembiochem : a European journal of chemical biology, 9(3), 389-400 (2008-01-29)
Bacterial quorum sensing is mediated by low molecular-weight signals and plays a critical role in both the pathogenesis of infectious disease and beneficial symbioses. There is significant interest in the development of synthetic ligands that can intercept bacterial quorum sensing
Grant D Geske et al.
Journal of the American Chemical Society, 129(44), 13613-13625 (2007-10-12)
Bacteria use a language of low molecular weight ligands to assess their population densities in a process called quorum sensing. This chemical signaling process plays a pivotal role both in the pathogenesis of infectious disease and in beneficial symbioses. There
相关内容
We study quorum sensing, how bacteria sense their density. Synthesized compounds modulate pathways, aiding research on infections in various hosts.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持