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Merck
CN

804347

Sigma-Aldrich

3-nitro-N-[(3S)-tetrahydro-2-oxo-furanyl]-Benzeneacetamide

别名:

LasR inhibitor, LuxR activator

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关于此项目

经验公式(希尔记法):
C12H12N2O5
化学文摘社编号:
分子量:
264.23
UNSPSC代码:
12352200
NACRES:
NA.22
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表单

solid

储存温度

−20°C

应用

PHL has varied activity depending on species, for example serving as either a strong LuxR-type receptor activator (e.g.: of LuxR in V. fischeri and of ExpR1 and ExpR2 in Pectobacterium carotovora) or a strong inhibitor (e.g.: of LasR in P. aeruginosa)

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Andrew G Palmer et al.
Chembiochem : a European journal of chemical biology, 12(1), 138-147 (2010-12-15)
Many bacteria use quorum sensing (QS) to regulate cell-density dependent phenotypes that play critical roles in the maintenance of their associations with eukaryotic hosts. In Gram-negative bacteria, QS is primarily controlled by N-acylated L-homoserine lactone (AHL) signals and their cognate
Grant D Geske et al.
Journal of the American Chemical Society, 129(44), 13613-13625 (2007-10-12)
Bacteria use a language of low molecular weight ligands to assess their population densities in a process called quorum sensing. This chemical signaling process plays a pivotal role both in the pathogenesis of infectious disease and in beneficial symbioses. There

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We study quorum sensing, how bacteria sense their density. Synthesized compounds modulate pathways, aiding research on infections in various hosts.

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