Potassium 4-fluorobenzoyltrifluoroborate

Potassium 4-fluorobenzoyltrifluoroborate belongs to the potassium acyltrifluoroborate (KAT) group. It can be synthesized from 1-(methoxy(4-fluorophenyl)methyl)-1H-benzotriazole.

Potassium 4-fluorobenzoyltrifluoroborate may be used in the synthesis of MIDA (N-methyliminodiacetic acid) 4-fluorobenzoylboronate. It may also be used in the synthesis of potassium O-(4-benzoyltrifluoroborate)-O′-methylpolyethylene glycols of varying molecular weights.

Potassium Acyltrifluroborates (KAT′s) are bench, air, and moisture stable reagents for rapid, chemoselective amide bond formations with hydroxylamines. These amide bond forming reactions proceed under aqueous conditions, without the need for coupling reagents or protecting groups. This product was introduced in collaboration with the Bode Research Group.