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Merck
CN

852279

2′-脱氧肌苷

99%

别名:

9-(2-脱氧-β-D-呋喃核糖基)次黄嘌呤

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关于此项目

经验公式(希尔记法):
C10H12N4O4
化学文摘社编号:
分子量:
252.23
EC Number:
212-964-1
UNSPSC Code:
12352103
PubChem Substance ID:
Beilstein/REAXYS Number:
33517
MDL number:
Assay:
99%
Form:
powder
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InChI key

VGONTNSXDCQUGY-RRKCRQDMSA-N

InChI

1S/C10H12N4O4/c15-2-6-5(16)1-7(18-6)14-4-13-8-9(14)11-3-12-10(8)17/h3-7,15-16H,1-2H2,(H,11,12,17)/t5-,6+,7+/m0/s1

SMILES string

OC[C@H]1O[C@H](C[C@@H]1O)n2cnc3C(=O)NC=Nc23

assay

99%

form

powder

functional group

ether, hydroxyl

Quality Level

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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L S Bazar et al.
Electrophoresis, 20(6), 1141-1148 (1999-06-25)
We introduce a novel experimental strategy for DNA mutation detection named the Mismatch Identification DNA Analysis System (MIDAS) [1, 2], which has an associated isothermal probe amplification step to increase target DNA detection sensitivity to attomole levels. MIDAS exploits DNA
Chia-Chia Lee et al.
DNA repair, 9(10), 1073-1079 (2010-08-11)
Deoxyinosine (dI) in DNA can arise from hydrolytic or nitrosative deamination of deoxyadenosine. It is excised in a repair pathway that is initiated by endonuclease V, the nfi gene product, in Escherichia coli. Repair was studied in vitro using M13mp18
Raphaelle Fanciullino et al.
Pharmaceutical research, 22(12), 2051-2057 (2005-10-14)
The aims of this study were to develop a stealth, pegylated liposomal formulation of 2'-deoxyinosine (d-Ino), a 5-fluorouracil (5-FU) modulator, to evaluate its efficacy in vitro and in tumor-bearing mice, and to study its pharmacokinetics in rats. After designing a
Kok Seong Lim et al.
Nature protocols, 1(4), 1995-2002 (2007-05-10)
Several studies examining DNA deamination have published levels of 2'-deoxyinosine that illustrated a large variation between studies. Most of them are the result of artifactual DNA deamination that occurs during the process of sample preparation, particularly acid hydrolysis. This protocol
Nobuyuki Horinouchi et al.
Applied microbiology and biotechnology, 71(5), 615-621 (2005-11-12)
2'-Deoxyribonucleosides are important as building blocks for the synthesis of antisense drugs, antiviral nucleosides, and 2'-deoxyribonucleotides for polymerase chain reaction. The microbial production of 2'-deoxyribonucleosides from simple materials, glucose, acetaldehyde, and a nucleobase, through the reverse reactions of 2'-deoxyribonucleoside degradation

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