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Merck
CN

852279

Sigma-Aldrich

2′-脱氧肌苷

99%

别名:

9-(2-脱氧-β-D-呋喃核糖基)次黄嘌呤

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关于此项目

经验公式(希尔记法):
C10H12N4O4
化学文摘社编号:
分子量:
252.23
Beilstein:
33517
EC 号:
MDL编号:
UNSPSC代码:
12352103
PubChem化学物质编号:
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质量水平

方案

99%

表单

powder

官能团

ether
hydroxyl

SMILES字符串

OC[C@H]1O[C@H](C[C@@H]1O)n2cnc3C(=O)NC=Nc23

InChI

1S/C10H12N4O4/c15-2-6-5(16)1-7(18-6)14-4-13-8-9(14)11-3-12-10(8)17/h3-7,15-16H,1-2H2,(H,11,12,17)/t5-,6+,7+/m0/s1

InChI key

VGONTNSXDCQUGY-RRKCRQDMSA-N

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jing Zhang et al.
Chemical communications (Cambridge, England), 46(37), 6986-6988 (2010-08-24)
A novel electrochemical biosensor for the genotyping/detection of single-nucleotide polymorphisms (SNPs) of trace oral-cancer salivary DNA based on junction probes containing 2'-deoxyinosine (dI) residues is described.
Min Dong et al.
Chemical research in toxicology, 19(1), 50-57 (2006-01-18)
Nitric oxide (NO) is a physiologically important molecule that has been implicated in the pathophysiology of diseases associated with chronic inflammation, such as cancer. While the complicated chemistry of NO-mediated genotoxicity has been extensively study in vitro, neither the spectrum
Kok Seong Lim et al.
Nature protocols, 1(4), 1995-2002 (2007-05-10)
Several studies examining DNA deamination have published levels of 2'-deoxyinosine that illustrated a large variation between studies. Most of them are the result of artifactual DNA deamination that occurs during the process of sample preparation, particularly acid hydrolysis. This protocol
Susen Hartmann et al.
Clinical chemistry, 52(6), 1127-1137 (2006-04-15)
Clinical presentation and disease severity in disorders of purine and pyrimidine metabolism vary considerably. We present a method that allows comprehensive, sensitive, and specific diagnosis of the entire spectrum of abnormalities in purine and pyrimidine metabolism in 1 analytical run.
Chia-Chia Lee et al.
DNA repair, 9(10), 1073-1079 (2010-08-11)
Deoxyinosine (dI) in DNA can arise from hydrolytic or nitrosative deamination of deoxyadenosine. It is excised in a repair pathway that is initiated by endonuclease V, the nfi gene product, in Escherichia coli. Repair was studied in vitro using M13mp18

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